Volume 17 Issue 7 - 2022
From the Zoo to the Clinic; New Ideas about Cancer
Paul Clayton*
Society of Integrated Medicine, Warsaw, Poland
*Corresponding Author: Paul Clayton, Society of Integrated Medicine, Warsaw, Poland.
Received: June 29, 2022; Published: June 30, 2022



Keywords: Peto; Pets; Animal Size; Cancer Epidemiology; Lifestyle; Chemoprevention; Modifiable Risk Factors

Text: Peto’s Paradox [1], named after the great epidemiologist and statistician Sir Richard Peto, is well known in cancer circles. If every cell has a similar chance of becoming cancerous (due to random DNA hits/mutations), then larger animals with longer life-spans and more cells in their bodies should have higher rates of cancer. The fact that they don’t, is the paradox.


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  29. Delicano RA., et al. “The shared risk of diabetes between dog and cat owners and their pets: register based cohort study”. British Medical Journal on JSTOR 371 (2020): m4337.
  30. Lo CH., et al. “Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study”. Gut3 (2021): 620-621.
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  39. Wallis C and Holcombe LJ. “A review of the frequency and impact of periodontal disease in dogs”. Journal of Small Animal Practice9 (2020): 529-540.
  40. https://www.youtube.com/watch?v=h1RYRJprFOY
  41. Personal experience. I recommend PlaqueOff, by Pro Den.
  42. Adams VJ., et al. “Methods and mortality results of a health survey of purebred dogs in the UK”. Journal of Small Animal Practice 51 (2010): 512-524.
  43. Dobson JM. “Breed-predispositions to cancer in pedigree dogs”. ISRN Veterinary Science (2013): 941275.
  44. https://www.ozy.com/true-and-stories/i-did-it-6-days-of-eating-dog-food/36846/
  45. https://drpaulclayton.eu/blog/volatile-characters/
  46. Thomas F., et al. “Rare and unique adaptations to cancer in domesticated species: An untapped resource?” Evolutionary Applications Open Access (2020).
Citation: Paul Clayton. “From the Zoo to the Clinic; New Ideas about Cancer”. EC Nutrition 17.7 (2022): 12-17.

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