Research Article
Volume 16 Issue 9 - 2021
Different Methods of Clay Application for Humans
Staniša Stojiljković*, Milena Stojiljković and Bojana Milićević
Faculty of Technology, University of Nis, Leskovac, Serbia
*Corresponding Author: Staniša Stojiljković, Faculty of Technology, University of Nis, Leskovac, Serbia.
Received: May 27, 2021; Published: August 28, 2021


Minerals are imperative for humanity. As a natural source of all minerals, clays can be beneficial to human health. The use of clay minerals for food, medicinal purposes, in pharmaceutical formulations, spas, beauty treatments is almost old as mankind. Clay has no toxic elements in concentrations that can harm a human body. Bentonite, montmorillonite, pascalite and other types of natural clays were applicable since prehistoric times. Concerning the physical and chemical composition of bentonite clay, it was useful as a cleaning agent for humans, mammals, birds, reptiles and insects. The aim of this work is examination of the clay applications in order to improve human health. The application of characterization analyses and thermal treatment were used for the characterization of bentonite clay, sampled from Prisjan, a village in Serbia. Considering historical development of clay, a relationship between clay and organic matter, the impact of clay on life development cycle, this work examines different methods of clay applications to improve our lives.


Keywords: Application; Clay; Bentonite; Humans; Health


  1. Mewis J and Macosko CW. “Suspension rheology”. In: Macosko CW., edition. Rheology: principles, measurements and applications. New York: VCH Pub (1994): 425-474.
  2. Stojiljković S. “MA Thesis, Mechanical Engineering Faculty, Nis, University of Nis (1984).
  3. Filipović A. “Thermal and acid activation of bentonite clay”. Unpublished Thesis, Faculty of Technology, Leskovac, University of Nis (2011).
  4. Carretero MI. “Clay minerals and their beneficial effects upon human health”. Applied Clay Science 21 (2002): 155-163.
  5. Stojiljković S. “A power of clay”. Faculty of Technology Leskovac (2005).
  6. Bergaya F., et al. “Handbook of Clay Science”. Developments in Clay Science (2006): 1-25.
  7. Bech J. “Les Terres Medicinals. Discurs per Reial Academia de Farma`cia de Barcelona”. edition. Reial Acade`mia de Farma`cia de Barcelona. Barcelona: CIRIT (1987): 105.
  8. Veniale F. “Le argille nelle terapie curative: dalla leggenda all’empirismo, fino ai tempi moderni”. Proceedings of the Argille per fanghi peloidi termali e per trattamenti dermatologici e cosmetici: Atti Simposio, 1999, Montecatini Terme,Mineralogica et Petrographica Acta, XLII (1999): 263-265.
  9. Simonton TC., et al. “Gelling properties of sepiolite versus montmorillonite”. Applied Clay Science 3 (1988): 165-176.
  10. Mpuchane S., et al. “Mineralogy of southern African medicinal and cosmetics clays and their effects on the growth of selected test microorganisms”. Fresenius Environmental Bulletin 15 (2008): 547-557.
  11. Knishinsky R. “The Clay Cure: Natural Healing from the Earth. Rochester: Healing Arts (1998).
  12. Stojiljković S., et al. “Changing the pH and Electrical Conductivity of the Suspension of Bentonite “. Proceedings of Addition of Polymers: Conference (EUROCLAY), Antaliya, Turkey (2011).
  13. Roksandić M., et al. “Interpersonal Violence at Lepenski Vir Mesolithic/Neolithic Complex of the Iron Gates Gorge (Serbia-Romania)”. American Journal of Physical Anthropology 129 (2006): 339-348.
  14. Viseras C., et al. “Uses of clay minerals in semisolid health care and therapeutic products”. Applied Clay Science 36 (2007): 37-50.
  15. Gabriel DM. “Vanishing and foundation creams”. In: Harry R G, edition. Harry's Cosmetology. London: Leonard Hill Books (1973): 83.
  16. Patel NK. “Pharmaceutical suspensions”. In: Lachman L., Lieberman HA., Kanig JL., editions. The Theory and Practice of Industrial Pharmacy. Philadelphia (1986): 479-501.
  17. Alexander P. “Sunscreen, Suntan and Sunburn Preparations”. In: Harry R G., ed. Harry's Cosmeticology. The Principles and Practice of Modern Cosmetics. London: Leonard Hill Books (1973): 103-328.
  18. Aguzzi C., et al. “Use of Clays as Drug Delivery Systems: Possibilities and Limitations”. Applied Clay Science 36 (2007): 22-36.
  19. Schexnailder P and Schmidt G. “Colloid and Polymer Science 287 (2009): 1.
  20. Brunet de Courssou L. “Study Group Report on Buruli ulcer treatment with clay”. Proceedings of the 5th WHO Advisory Group Meeting on Buruli ulcer, World Health Organization, Geneva, Switzerland (2002).
  21. Williams LB., et al. “Chemical and mineralogical characteristics of French green clays used for healing”. Clays and Clay Minerals 56 (2008): 437-452.
  22. Bonglaisin N and Mbofung DN. “Lantum Intake of lead: cadmium and mercury in kailon eating: a quality assessment”. Journal of Medical Science 7 (2011): 267-273.
  23. Ngole M., et al. “Physicochemical characteristics of geophagic clayey soils from South Africa and Swaziland”. African Journal of Biotechnology 36 (2010): 5929-5930.
  24. Guggenheim S and Martin RT. “Definition of clay and clay mineral. Joint report of the AIPEA nomenclature and CMS nomenclature commitees”. Clays and Clay Minerals 43 (1995): 255-256.
  25. Robertson RHS. “Fuller's Earth”. A History of calcium montmorillonite. Volturna, Press, U.K (1986).
  26. Odom IE. ''Smectite clay Minerals: Properties and Uses''. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 311 (1984): 391-409.
  27. Miller SL and Urey HC. “Organic Compound Synthesis on the Primitive Earth”. Science 130 (1959): 245-251.
  28. Miller SL. “A Production of Amino Acids under Possible Primitive Earth Conditions”. Science 117 (1953): 528-529.
  29. Shimoyama A., et al. “Synthesis of Amino Acids under Primitive Earth Conditions in the Presence of Clay”. In: Noda NH., edition. Origin of Life. Tokyo: Center for Academic Publisher (1978): 95-99.
  30. Yuasa S. “Polymerization of Hydrogen Cyanide and Production of Amino Acids and Nucleic Acid Bases in the Presence of Clay Minerals–In Relation to Clay and the Origin of Life”. Nendo Kagaku 29(1989): 89-96.
  31. Hashizume H. “Clay Minerals in Nature - Their Characterization, Modification and Application". In: Valaskova M., edition. Role of Clay Minerals in Chemical. Japan: In Tech (2012).
  32. Friebele E., et al. “Adsorption of protein and non-protein amino acids on a clay mineral: a possible role of selection in chemical evolution”. Journal of Molecular Evolution 16 (1980): 269-278.
  33. Stumpf J. “Bolus fur medizinische Anwenduno, Darmstadt (1916).
  34. Schimoyama A. “Clay minerals and amino acids in relation to the origin of life”. Journal of the Clay Science Society of Japan 21 (1981): 93-101.
  35. Nelda P. “Beauty worlds: cosmetics and body decoration”.
  36. Baeke V. “A la recherche du sens du bwami. Au fil d'une collection lega pas comme les autres”. Royal Museum for Central Africa (2009).
Citation: Staniša Stojiljković., et al. “Different Methods of Clay Application for Humans”. EC Nutrition 16.9 (2021): 36-45.

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