Research Article
Volume 13 Issue 8 - 2021
Time of Arrival at Oñativia Hospital After a Cerebrovascular Attack (CVA)
Isaac C*, Cruz D, Basile P, Dognibene G, Martino A and Macia J
Hospital Oñativia, Rafael Calzada, Prov. Bs As, Argentina
*Corresponding Author: Isaac C, Department of Neurology, Hospital Oñativia, Rafael Calzada, Prov. Bs As, Argentina.
Received: August 04, 2021; Published: August 27, 2021


CVA is the leading cause of disability and the second cause of death in the world and in Argentina it is the third leading cause of death. Once fast acting occurs, decreases the consequences (therapeutic window 3 - 4.5h (TW): “The time is brain”). In our hospital environment we do not have intravenous thrombolysis with rtPA (IT) for CVA ischemic. The only hospital that counts with medication in the region is the Hospital “El Cruce” of Florencio Varela. Our studio shows that the majority of patients (102: 77%) arrive at Hospital Oñativia in the TW to receive IT to avoid the complications that occur not receiving treatment. According to the bibliography with the IT in our study: 1. 33% of the patients who arrived before 3 hours (33.66 patients) would not sequels. 2. 75% of the patients who arrived before 3 hours would be left with definitive sequelae (56,25 patients). 3. 25% of the patients who arrived before 3 hours will not be able to resume never professional activity (18.75 patients). 4. Mortality of patients in our serious study: 1) Mortality at 7 days: 6.9% (7 patients); 2) Mortality at 30 days: 12.6% (12.9 patients); 3) Mortality at 1 year: 23.6% (24.1 patients).

Keywords: Cerebrovascular Attack (CVA); Intravenous Thrombolysis (IT); Therapeutic Window (TW)


  1. Víctor Ingrassia, Diario La Nation. “Every 4 minutes a person suffers a stroke in Argentina, Society, Health, Argentina (2015).
  2. Dr Ana Maria Atallah., et al. “Consensus for the acute diagnosis and treatment of stroke ischemic. Stroke Council - Argentine Society of Cardiology”. Revista Argentina de Cardiología5 (2012).
  3. Dr Mandile Marcela and Dra Torres Mariela. “Cost-benefit in lithic thrombus treatment in ischemic stroke”. German Hospital (2010).
  4. Pablo loli., et al. “Thrombolysis in ischemic stroke: analysis of the “Timeline” line in the stage hospitable. Private hospital of the Community, Mar del Plata, Bs As, Argentina.
  5. Hernán Bayona O., et al. “Agreement in the performance of triage between nursing and neurology in patients with ischemic stroke in a university hospital: a cross-sectional study in a Bogotá hospital”. Revista Colombiana de Enfermería10 (2015): 57-63.
  6. Analysis of the times in the prehospital care of the CVA. Dr Paul Barberousse. Montevideo.
  7. Hernan F Bayona O., et al. “Usefulness of the stroke code in patients with acute stroke: comparison of two periods of time”. Acta Neurológica Colombiana4 (2014): 256-262.
  8. “Behavior of cerebrovascular disease in the care unit intensive of the central Havana municipality. 2004 - 2005 ". Dra Heydi Flores Pruning Machine and cols.
  9. J Perez-Nellar., et al. “Delay in the arrival of patients with subarachnoid hemorrhage to a hospital tertiary”. Revneurology 10 (2009): 542-528.
  10. Dr Luis Gomez Peña., et al. “Chain of survival of stroke: a challenge in today's medicine”. Revista Cubana de Medicina Intensiva y Emergencias1 (2007): 600-613.
  11. José Luis Astorga Castillo. “Clinical epidemiological aspects of cerebrovascular disease. Service Arzobispo Loayza hospital emergency”. Thesis. Lima - Peru (2005).
  12. Luis Valle Valverde., et al. “Ischemic cerebrovascular attack with thrombolysis criteria in the department of Edgardo RebagliatiMartins Hospital emergency - ESSALUD. August December 2000. Thesis UNMSM (Universidad Nacional Mayor de San Frames) (2000).
  13. Pia Chatterjee MD., et al. “Emergency Department Crowding and Time to Care in Patients With Acute Stroke”. Stroke 42 (2011): 1074-1080.
  14. Llana M Ruff MD., et al. “Improving Door-To-Needle Times. A Single Center Validation of the Target Stroke Hypothesis”. Stroke 45 (2014): 504-508.
  15. Bernadette Boden-Albala DrPH., et al. “Comparison of Acute Stroke Preparedness Strategies to Decrease Emergency Department Arrival Time in a Multiethnic Cohort. The Stroke Warning Information and Faster Treatment Study”. Stroke 46 (2015): 1806-1812.
  16. T Belzunegui. Predictive Value of the Ontario Prehospital Stroke Screening Tool (Ontario Prehospital Stroke Screening Tool) for the identification of pa … Prehospital Emergency Care. Spanish Edition 2.3 (2009).
  17. Dawn O Kleindorfer MD., et al. “Community Socioeconomic Status and Prehospital Times in Acute Stroke and Transient Ischemic Attack. Do Poorer Patients Have Longer Delays From 911 Call to the Emergency Department”. Stroke 37 (2006): 1508 -1513.
  18. Kathryn M Rose MD., et al. “Predictors of Time From Hospital Arrival to Initial Brain – Imaging Among Suspected Stroke Patients. The North Carolina Collaborative Stroke Registry”. Stroke 39 (2008): 3262 -3267.
  19. Gregg C Fonarow MD., et al. “Improving Door-to-Needle Times in Acute Ischemic Stroke. The Design and Rationale for the American Heart Association / American Stroke Association´s Target: Stroke Initiative”. Stroke 42 (2011): 2983-2989.
  20. Nerses Sanossian MD. “Routing Ambulances to Designated Centers Increases Access to Stroke Center Care and Enrollment in Prehospital Research”. Stroke 46 (2015): 2886-2890.
  21. David Tong MD., et al. “Times From Symptom Onset to Hospital Arrival in the Get With The Guidelines-Stroke Program 2002 to 2009. Temporal Trends and Implications”. Stroke 43 (2012): 1912-1917.
  22. Osei Agyeman MD., et al. “Time to Admission in Acute Ischemic Stroke and Transient Ischemic Attack”. Stroke 37 (2006): 963-966.
  23. Kjell Asplund MD., et al. “Effects of extending the Time Window of thrombolysis to 4,5hs. Observations in the Swedish Stroke Register (Risks-Stroke)”. Stroke 42 (2011): 2492-2497.
  24. Cristina Yustes Biribay. "Analysis of prehospital care to the stroke code in Asturias" (2013).
  25. Krassen Nedeltchev., et al. “Pre-and in-Hospital Delays From Stroke Onset to Intra-arterial Thrombolysis”. Stroke 34 (2003): 1230-1234.
  26. Per Wester and MD and Cols. “Factors Associated With Delayed Admission to Hospital and In-Hospital Delays in Acute Stroke and TIA”. Stroke 30 (1999): 40-48.
  27. Dr Anna Faggi., et al. “Defining the efficiency and effectiveness variables of a Stroke unit. Fundacion Dr JR Villavicencio Yearbook (2006): 081-088.
  28. Sandy Middleton., et al. “Arrival Time to Stroke Unit as Crucial a Measure as Arrival Time to Emergency Department”. Stroke 39 (2008): e5.
  29. Toshiyuki Uehara MD., et al. “Factors Associated With Onset-to-Door Time in Patients With Transient Ischemic Attack Admitted to Stroke Centers”. Stroke 45 (2014): 611-613.
Citation: Isaac C, et al. “Time of Arrival at Oñativia Hospital After a Cerebrovascular Attack (CVA)”. EC Neurology 13.9 (2021): 13-18.

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