Mini Review
Volume 13 Issue 8 - 2021
Therapeutic Role of Vagal Nerve Stimulation in Cerebral Palsy: Quantitative Electroencephalographic Evidence
Harinder Jaseja*
Consultant, Vellore EEG Center, Gwalior, India
*Corresponding Author: Harinder Jaseja, Consultant, Vellore EEG Center, Gwalior, India.
Received: June 21, 2021; Published: July 29, 2021




Abstract

Vagal nerve stimulation (VNS) has been proposed earlier as a therapeutic intervention in patients with cerebral palsy (CP) for improvement in their seizure-profile, cognitive status and quality of life based on which CP has been included in the list of therapeutic indications for VNS. The proposal is based on dual-effect (suppression of seizures and interictal epileptiform discharges) of VNS. This brief paper presents a statistical analysis of VNS induced electroencephalographic (EEG) effects from recent studies, which supports the therapeutic role of VNS in CP.

Keywords: Cognitive Status; EEG-Desynchronization; Interictal Epileptiform Discharges; Quality of Life; VNS Policy

References

  1. Jaseja H. “Vagal nerve stimulation: exploring its efficacy and success for an improved prognosis and quality of life in cerebral palsy patients”. Clinical Neurology and Neurosurgery 110 (2008): 755-762.
  2. Kuba R., et al. “Effect of vagal nerve stimulation on interictal epileptiform discharges: a scalp EEG study”. Epilepsia 43 (2002): 1181-1188.
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  5. Jaseja H. “EEG-desynchronization as the major mechanism of anti-epileptic action of vagal nerve stimulation in patients with intractable seizures: clinical neurophysiological evidence”. Medical Hypotheses5 (2010): 855-856.
  6. http://www.aetna.com/cpb/medical/data/100_199/0191.html
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  8. Engineer CT., et al. “Vagus nerve stimulation as a potential adjuvant to behavioral therapy for autism and other neurodevelopmental disorders”. Journal of Neurodevelopmental Disorders 9 (2017): 20.
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  10. Kuba R., et al. “Effect of chronic vagal nerve stimulation on interictal epileptiform discharges”. Seizure 19 (2010): 352-355.
  11. Bodin C., et al. “Responders to vagus nerve stimulation (VNS) in refractory epilepsy havereduced interictal cortical synchronicity on scalp EEG”. Epilepsy Research 113 (2015): 98-103.
  12. Yokoyama R., et al. “The immediate effects of vagus nerve stimulation in intractable epilepsy: An Intraoperative electrocorticographic analysis”. Neurologia Medico-Chirurgica5 (2020): 244-251.
Citation: Harinder Jaseja. “Therapeutic Role of Vagal Nerve Stimulation in Cerebral Palsy: Quantitative Electroencephalographic Evidence”. EC Neurology 13.8 (2021): 76-78.

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