Research Article
Volume 13 Issue 7 - 2021
Spinal Neurofibromas: Literature Review and Surgical Outcome
Farooq Azam1, Adnan Khaliq1*, Mumtaz Ali1 and Bipin Chaurasia2
1Department of Neurosurgery, MTI/Lady Reading Hospital, Peshawar, Pakistan
2Department of Neurosurgery, BSMMU, Bangladesh
*Corresponding Author: Adnan Khaliq, Department of Neurosurgery, MTI/Lady Reading Hospital, Peshawar, Pakistan.
Received: October 11, 2020; Published: June 22, 2021


Objective: To determine the overall clinical outcome, specific features of spinal neurofibromas following surgery.

Background: Among all primary spinal neoplasms, approximately one-third are neurofibromas. Its incidence, clinical presentation, operative techniques and outcome of surgical resection need be studied thoroughly.

Methodology: This Retrospective study was conducted in department of Neurosurgery Lady Reading Hospital Peshawar, Pakistan from January 2016 to December 2016. Medical records of patients was revised and searched. Inclusion criteria was all symptomatic newly diagnosed and recurrent spinal neurofibromas. Exclusion criteria was asymptomatic spinal neurofibromas found as incidental finding. Patients were followed upto 3 months post operatively. The demographic data, clinical, radiological and histological details of patients were analyzed to assess and evaluate the predictive factors that affect post-operative clinical outcome. Diagnosis was made on clinical features, contrast enhanced spinal magnetic resonance imaging (MRI) and confirmed by histopathology of the lesion. Gross Total Microsurgical resection was carried out in all cases through a posterior approach. Post-Operative assessment was done in terms of clinical, neurological improvement of symptoms and surgical complications.

Results: Total number of patients were (15) harboring spinal neurofibroma. Mean age was (55 years). There were (8) males and (7) females patients. Neurofibroma was found in cervical spine in 11 cases (72%) and in thoracic spine in 4 cases (28%). Fresh cases were (13) and recurrent cases were (2).

Clinical presentations of patients were gait disturbance 14 cases (93%), Motor deficit/weakness 12cases (80%), sensory deficit 12 cases (80%), radicular pain 9 cases (60%), local spinal pain in 7 cases (47%), sphincter dysfunction in 9 cases (60%). The most common site of spinal neurofibromas was cervical region. All tumors were intramural extramedullary. All patients were thoroughly observed for 12 months. Post-operative neurological improvement was observed in 13 patients (87%). There was no operative mortality. None of the patient was subjected to adjuvant radiotherapy.

Conclusion: Spinal neurofibromas are benign tumors. Surgical excision can be safely done without having any post-operative deficits. Availability of many different tools and good microscope has made complete removal of tumors with no further recurrences.


Keywords: Neurofibroma; Spinal Tumors; Surgical Outcome


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Citation: Adnan Khaliq., et al. “The Vitiated Highbrow- Brain in COVID-19”. EC Neurology 13.5 (2021): 37-42.

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