Mini Review
Volume 12 Issue 10 - 2020
The Application of Fullerene Materials in Neurological Diseases and Disorders
Nicholas A Kerna1* and John V Flores2,3
1SMC–Medical Research, Thailand
2Beverly Hills Wellness Surgical Institute, USA
3Orange Partners Surgicenter, USA
*Corresponding Author: Nicholas A Kerna, POB47 Phatphong, Suriwongse Road, Bangkok, Thailand 10500.
Received: August 10, 2020; Published: September 15, 2020




Abstract

Fullerene materials are composed of carbon atoms, and are compatible with biological systems in humans and animals. They have been investigated for applications in humans for nearly fifty years. Fullerene materials reduce free radicals in cells, provide anti-inflammatory effects, and inhibit tumor growth. However, the primary antioxidant benefit of fullerene materials might be the activation of nuclear factor (erythroid-derived 2) factor 2 (Nrf2). Fullerenol nanoparticles reduce the sequelae of brain injuries caused by ischemia. Fullerene materials delay the functional deterioration of neurons and reduce the symptoms and prevalence of diabetic neuropathy. Due to their mechanical and electrical properties, nanocarbon materials stimulate cells and neurons and have been used as frameworks in neuron stem growth and neuronal development. Fullerene materials can be used for the prevention or treatment of specific neurological disorders due to their complementary effects, biocompatibility, and low toxicity in humans. However, fullerene materials’ safety, manufacture, and dosage should be further evaluated and established for their therapeutic use in humans.

Keywords: Allotrope; Diabetic Neuropathy; Free Radical; Fullerene; Stroke

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Citation: Kerna NA, Flores JV. The Application of Fullerene Materials in Neurological Diseases and Disorders. EC Neurology 12.9 (2020): 11-15.

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