Case Report
Volume 12 Issue 9 - 2020
Stroke in Young with Coronavirus Disease 2019 (Covid-19), a Case Report during Pandemic
Naif Al Zahrani, Sultan Al Zahrani and Farah Aleisa*
Neuroscience Department, King Fahad Specialist Hospital, Dammam, KSA
*Corresponding Author: Farah Aleisa, Neuroscience Department, King Fahad Specialist Hospital, Dammam, KSA.
Received: July 23, 2020; Published: August 11, 2020




Abstract

Background: COVID-19 (Coronavirus Disease 2019) infection ranging from mild disease to severe life-threatening acute respiratory distress syndrome (ARDS) and severe pneumonia. Severe infections were reported to have multiple neurological complications in 36% of patients, neurological complications like peripheral neuropathy and encephalitis and cerebrovascular disease are more reported recently.

Recent Updates: Case series at one hospital in New York, five cases of large-vessel stroke in patients younger than 50 years of age, two of them don’t have vascular risk factors, their deficits were severe, all patients had elevated C-reactive protein and three had significant elevated D-dimer levels.

Case Presentation: We are reporting a patient who had cerebrovascular complication diagnosed 3 weeks after the onset of respiratory illness, CT brain (computed tomography scan of brain) showed multiple subacute embolic infracts, the larger one in the left hemisphere, CT angiogram revealed large left ICA (internal carotid artery) and MCA (middle cerebral artery) tandem occlusion, immediate anticoagulation was started low molecular weight heparin to reduce the risk of thrombotic disease.

Conclusion and Future Direction: The apparently high incidence of cerebrovascular disease in patients with COVID-19, with predominantly large vessel disease and markers of a highly prothrombotic state suggest a causal relationship, and the fact that most stroke patients have other risk factors, mean that it is hard to be sure about causation, therefore case control studies are needed.

Keywords: Stroke; Young; COVID-19; Thrombosis; Anticoagulation

References

  1. Dong E., et al. “An interactive web-based dashboard to track COVID-19 in real time”. The Lancet Infectious Diseases 20 (2020): 533-534.
  2. Centers for Disease Control and Prevention. “How CDC classifies flu severity” (2020).
  3. Mao L., et al. “Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China”. JAMA Neurology 6 (2020): 1-9.
  4. Varatharaj A., et al. “UK-wide surveillance of neurological and neuropsychiatric complications of COVID-19: the first 153 patients”. Social Science Research Network (2020).
  5. Li Y., et al. “Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study” (2020).
  6. Lodigiani C., et al. “Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy”. Thrombosis Research 19 (2020): 9-14.
  7. Thomas J Oxley., et al. “Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young, NY, USA”. The New England Journal of Medicine (2020).
  8. Beyrouti R., et al. “Characteristics of ischaemic stroke associated with COVID-19”. Journal of Neurology, Neurosurgery, and Psychiatry (2020).
  9. Boehme AK., et al. “Influenza-like illness as a trigger for ischemic stroke”. Annals of Clinical and Translational Neurology 4 (2018): 456-463.
  10. Boehme AK., et al. “Stroke risk factors, genetics, and prevention”. Circulation Research 3 (2017): 472-495.
  11. Brit Lon MD., et al. “Cardiovascular complications in COVID-19”. American Journal of Emergency Medicine 7 (2020): 1504-1507.
Citation: Farah Aleisa., et al. “Stroke in Young with Coronavirus Disease 2019 (Covid-19), a Case Report during Pandemic”. EC Neurology 12.9 (2020): 31-34.

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