Mini Review
Volume 12 Issue 8 - 2020
A Short Glance at Oral Health and Depression
Jianliang Zhu1, Sunqiang Hu2, Fengchun Hu3 and Yun-Feng Zhang4*
1Department of Endodontics, School and Hosptial of Stomatological, Wenzhou Medical University, Wenzhou, China
2Department of Oral and Maxillofacial Surgery, School and Hosptial of Stomatological, Wenzhou Medical University, Wenzhou, China
3Department of Stomatology, The People’s Hospital of Dongying, Dongying, Shandong, China
4Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
*Corresponding Author: Yun-Feng Zhang, Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Received: July 08, 2020; Published: July 28, 2020


Depression is one severe neuropsychiatric disorder, the occurrence of which is resulted from genetic and environmental factors. Compared to other fruitful studies, relatively fewer studies are available for the association between oral health status and depression. Here we briefly summarized the current status regarding oral health and depression, aiming to highlight the importance of good oral health and hopefully provide some insights into clinical therapy of depression. Oral health is increasingly considered as an important public health concern, and oral health problems are closely associated with depression. Multiple studies strongly indicate the bi-directional relationship between oral health and depression. The positive association between depression and oral diseases further emphasizes that the efficient management of depressed patients with oral problems should be considered from different aspects. The reciprocally complicated interactions between poor oral health and depression also make it imperative to put more efforts to clarify the underlying mechanisms regarding oral health problems-induced depression. The great changes in gut microbiota composition induced by poor oral health can potentially induce dysfunctions in immune system and abnormal communication between gut and brain, further leading to depressive symptoms. In view of such a complicated association between oral health status and depression, more work are warranted to decipher the underlying mechanism in the pathogenesis of poor oral health-induced depression.

Keywords: Oral Health Problems; Antidepressant Medications; The Pathogenesis of Depression


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Citation: Yun-Feng Zhang., et al. “A Short Glance at Oral Health and Depression”. EC Neurology 12.8 (2020): 177-182.

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