Research Article
Volume 12 Issue 7 - 2020
Relationship between Amount of Exercise and Fatigue in People with Parkinson’s Disease
RuiPing Xia*, Thomas J Ronck, Ryan A Sanft and Ross P Eason
Department of Physical Therapy, Franklin Pierce University, Goodyear, AZ, USA
*Corresponding Author: RuiPing Xia, Department of Physical Therapy, Franklin Pierce University, Goodyear, AZ, USA.
Received: June 05, 2020; Published: June 30, 2020


Fatigue is one of the most debilitating symptoms in Parkinson’s disease (PD). It has been identified as an unmet need by the PD community due to limited understanding of fatigue. Fatigue likely not only limits patient’s participation in activity but also hinders patients’ compliance in therapy. Accumulating evidence suggests that exercise may be effective in management of PD-fatigue. The objective of this study was to examine the relationship between exercise and fatigue in individuals with PD. Further, the impact of depression and disease history on fatigue was also investigated. This was an observational, cross-sectional study. One hundred and thirty-one (131) patients participated in this survey research by filling in the Parkinson’s Fatigue Scale (PFS) and providing information about their weekly exercise duration, history of PD, and with or without a clinical depression. Pearson correlation analysis was applied to examine the relationship between weekly exercise duration expressed in 1/minute and PFS score. T-tests were performed to compare fatigue between participants with and without clinical depression as well as between participants at early and advanced stages of PD. A significant correlation was observed between the inversed weekly exercise duration (1/minute) and fatigue (r = 0.267; P = 0.02). Less fatigue was associated with increased physical activity. Further, a significant difference was found in fatigue level between patients with and without depression (P = 0.02). There was no difference in fatigue between the early and the advanced stages of PD groups (P = 0.23). The findings of this study support that an adequate amount of exercise and physical activity may be an effective approach to managing PD-fatigue and improving quality of life in individuals with PD.

Keywords: Parkinson’s Disease; Fatigue; Physical Activity; Exercise; Association


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Citation: RuiPing Xia., et al. “Relationship between Amount of Exercise and Fatigue in People with Parkinson’s Disease”. EC Neurology 12.7 (2020): 58-66.

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