Research Article
Volume 12 Issue 3 - 2020
Non Motor Symptoms and their Impact on Quality of Life in Moroccan Patients with Parkinson Disease
Hajar Elyachkouri1*, Najib Kissani1, Mohammed Khaled Choulli2 and Mohammed Chraa1
1Neurology Department, Mohammed VI University Hospital, Kadi Ayad Medical School University, Marrakesh, Morocco
2Physiology Department, Kadi Ayad University, Marrakesh, Morocco
*Corresponding Author:Hajar Elyachkouri, Neurology Department, Mohammed VI University Hospital, Kadi Ayad Medical School University, Marrakesh, Morocco.
Received: January 24, 2020; Published:February 17, 2020


Patients with Parkinson disease are more impaired by Non-motor symptoms (NMS) than motor symptoms, especially in advanced stages. Unfortunately, in most cases, it is unrecognized. NMS are important determinant of disability and quality of life in patients with Parkinson disease (PD). This is a prospective observational study conducted in the neurology department of Mohammed VI university hospital, on NMS in Moroccan patients with Parkinson disease. We report 115 patients (Males 61.5% mean age 59.1years) diagnosed over a period of 18 months. Patients were administered detailed questionnaires by a neurologist. The mean age of onset was 53.71 (ranged from 23 to 76 years). Pain (60.3%), constipation (59%), urinary urgency (52.6%), sleep disturbances mainly insomnia (57.7), and depression (47.4%), were the most frequent NMS in our cohort, while hallucinations (29.5%), diplopia (12.8%) and memory impairment (30.8%) were less frequent.

There was a difference between males and females on the distribution of NMS, depressed mood, anxiety and sleep problems were more common in females, while urinary disorders, constipation, sexual dysfunction were more common in males. NMS are positively correlated to the H&Y stage and to duration of the disease.

We used the Parkinson’s disease quality of life questionnaire Summary Index score (PDQ39IS) to assess the impact on quality of life in patients. Our results showed that the impact affected mainly the emotional well-being (47, 81%). Mobility was affected in second place (44.13%), followed by daily activities (42, 9%).

Keywords: Parkinson Disease; Non-Motor Symptoms; Quality of Life; NMSS; PDQ3; Moroccan Cohort


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Citation: Hajar Elyachkouri.., et al. “Non Motor Symptoms and their Impact on Quality of Life in Moroccan Patients with Parkinson Disease”. EC Neurology 12.3 (2020): 01-10.

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