Review Article
Volume 16 Issue 2 - 2020
Diabetes Complications among Elderly in Family Practice
Sharifa Salem Alshehri1*, Lamees Yahya Saeed Ayedh2, Ibrahim Khaled Mohammed Ameen3, Heba Abdulaziz Ali Nawaz4, Raghad Mohammed Nasser Asiri5, Helal Jarallah Alharthi‏6, Moatasem Mohammed Modhish7, Ali Omar Alshargi8, Abdullah Ali Alshawaf9, Mohammad Abdullah Kabli10 and Mohammed Ibrahim Mufti11
1Consultant Family Medicine, Primary Health Care, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
2King Khalid University, Saudi Arabia
3Umm Al-Qura University, Saudi Arabia
4Forensic Center in Medina, Saudi Arabia
5Abha Maternity and Children Hospital, Saudi Arabia
6King Faisal Medical Complex-Taif, Saudi Arabia
7Dr. Soliman Fakeeh Hospital, Saudi Arabia
8Ibn Sina National College for Medical Studies, Saudi Arabia
9Baqaiq Primary Health Care Center, Saudi Arabia
10King Abdull Aziz Hospital in Jeddah, Saudi Arabia
11Madinah General Hospital MHG in Medina City, Saudi Arabia
*Corresponding Author: Sharifa Salem Alshehri, Consultant Family Medicine, Primary Health Care, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia.
Received: January 07, 2020; Published: January 09, 2020




Abstract

Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resistance to peripheral actions of insulin, or both. Persistent hyperglycemia in uncontrolled diabetes can cause several complications, both acute and chronic. Diabetes is one of the leading causes of cardiovascular disease (CVD), blindness, kidney failure, and amputation of lower limbs. 

Aim: In this review, we will look into the complications of acute respiratory infection in elderly population. 

Methodology: The review is comprehensive research of PUBMED since the year 2002 to 2019. 

Conclusion: Diabetes should be prevented among older adults, or controlled to halt or slow the progression to otherwise inevitable complications, the public health community needs to develop, evaluate, and expand the reach of effective, targeted interventions that address the specific needs of older adults with or at risk for diabetes. Existing public health programs instituted to reach older diabetic patients may need to be modified to fully address their complex, specific needs and functional statuses, while remaining relevant to their interests and to the social and economic contexts in which they live. Possible modifications to these programs include greater use of lifestyle interventions, which have shown impressive early results.

Keywords: Diabetes Mellitus; Complications; Elderly

References

  1. Malek R., et al. “Diabetes and Ramadan: A multicenter study in Algerian population”. Diabetes Research and Clinical Practice 150 (2019): 322-330.
  2. Cowie CC., et al. “Full accounting of diabetes and pre-diabetes in the U. S. population in 1988-1994 and 2005-2006”. Diabetes Care 32.2 (2009): 287-294.
  3. Boyle JP., et al. “Projection of diabetes burden through 2050: impact of changing demography and disease prevalence in the U.S”. Diabetes Care 24 (2001): 1936-1940.
  4. Huang ES., et al. “Projecting the future diabetes population size and related costs for the US”. Diabetes Care 32.12 (2009): 2225-2229.
  5. Rossello X., et al. “Risk prediction tools in cardiovascular disease prevention: A report from the ESC Prevention of CVD Programme led by the European Association of Preventive Cardiology (EAPC) in collaboration with the Acute Cardiovascular Care Association (ACCA) and the Association of Cardiovascular Nursing and Allied Professions (ACNAP)”. European Heart Journal: Acute Cardiovascular Care 25 (2019): 2048872619858285.
  6. Gregg EW., et al. “Diabetes and physical disability among U.S. adults”. Diabetes Care 23 (2000): 1272-1277.
  7. Chentli F., et al. “Diabetes mellitus in elderly”. Indian Journal of Endocrinology and Metabolism 19.6 (2015): 744-752. 
  8. Choi YJ and Chung YS. “Type 2 diabetes mellitus and bone fragility: Special focus on bone imaging”. Osteoporos Sarcopenia 2.1 (2016): 20-24.
  9. Picke AK., et al. “Update on the impact of type 2 diabetes mellitus on bone metabolism and material properties”. Endocrine Connections 8.3 (2019): R55-R70.
  10. Carrillo-Larco RM., et al. “The risk of mortality among people with type 2 diabetes in Latin America: A systematic review and meta-analysis of population-based cohort studies”. Diabetes/Metabolism Research and Reviews 35.4 (2019): e3139.
  11. Kempegowda P., et al. “Managing hypertension in people of African origin with diabetes: Evaluation of adherence to NICE Guidelines”. Primary Care Diabetes 13.3 (2019): 266-271.
  12. Willis M., et al. “Conducting and interpreting results of network meta-analyses in type 2 diabetes mellitus: A review of network meta-analyses that include sodium glucose co-transporter 2 inhibitors”. Diabetes Research and Clinical Practice 148 (2019): 222-233.
  13. American Diabetes Association. “Standards of medical care in diabetes-2012”. Diabetes Care 35.1 (2012): S11-S63.
  14. Hussain S and Chowdhury TA. “The Impact of Comorbidities on the Pharmacological Management of Type 2 Diabetes Mellitus”. Drugs 79.3 (2019): 231-242..
  15. Piette JD and Kerr EA. “The impact of comorbid chronic conditions on diabetes care”. Diabetes Care 29 (2006): 725-731.
  16. Chentli F., et al. “Diabetes mellitus in elderly”. Indian Journal of Endocrinology and Metabolism 19.6 (2015): 744-752. 
  17. Motta M., et al. “Cardio-cerebrovascular complications in elderly with diabetes”. Archives of Gerontology and Geriatrics 44.3 (2007): 261-269. 
  18. Araki A., et al. “Low well-being is an independent predictor for stroke in elderly patients with diabetes mellitus”. Journal of the American Geriatrics Society 52.2 (2004): 205-210.
  19. Kalyani RR., et al. “Association of diabetes, comorbidities, and A1C with functional disability in older adults: results from the National Health and Nutrition Examination Survey (NHANES), 1999-2006”. Diabetes Care 33.5 (2010): 1055-1060.
  20. Kuswardhani RA and Suastika K. “Age and homocystein were risk factor for peripheral arterial disease in elderly with type 2 diabetes mellitus”. Acta Medica Indonesiana 42.2 (2010): 94-99.
  21. Kronmal RA., et al. “Mortality in pharmacologically treated older adults with diabetes: the Cardiovascular Health Study, 1989-2001”. PLoS Medicine 3.10 (2006): e400.
  22. Goraya TY., et al. “Coronary atherosclerosis in diabetes mellitus: a population-based autopsy study”. Journal of the American College of Cardiology 40.5 (2002): 946-953.
  23. Caspersen CJ., et al. “Aging, diabetes, and the public health system in the United States”. American Journal of Public Health 102.8 (2012): 1482-1497. 
  24. Chawla A., et al. “Microvasular and macrovascular complications in diabetes mellitus: Distinct or continuum?”. Indian Journal of Endocrinology and Metabolism 20.4 (2016): 546-551. 
  25. Fong DS., et al. “Diabetic retinopathy”. Diabetes Care 27 (2004): 2540-2553.
  26. Wong TY., et al. “Retinal microvascular abnormalities and incident stroke: The atherosclerosis risk in communities study”. Lancet 358 (2001): 1134-1140.
  27. Zhang X., et al. “Prevalence of diabetic retinopathy in the United States, 2005-2008”. The Journal of the American Medical Association 304.6 (2010): 649-656.
  28. Kalsekar ID., et al. “The effect of depression on health care utilization and costs in patients with type 2 diabetes”. Managed Care Interface 19.3 (2006): 39-46. 
  29. "Guidelines Abstracted from the American Geriatrics Society Guidelines for Improving the Care of Older Adults with Diabetes Mellitus”. JAGS 61 (2013): 2020-2026.
  30. Maraldi C., et al. “Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study”. Archives of Internal Medicine 167.11 (2007): 1137-1144.
  31. Ghanavati T., et al. “Functional balance in elderly with diabetic neuropathy”. Diabetes Research and Clinical Practice 96.1 (2012): 24-28.
  32. Unnikrishnan RI., et al. “Prevalence and risk factors of diabetic nephropathy in an urban South Indian population. The Chennai Urban Rural Epidemiology Study (CURES 45)”. Diabetes Care 30 (2007): 2019-2024. 
  33. Trevisan R., et al. “Lipids and renal disease”. Journal of the American Society of Nephrology 17.4.2 (2006): S145-147.
  34. Vinik AI., et al. “Diabetic neuropathy in older adults”. Clinics in Geriatric Medicine 24.3 (2008): 407-435.
  35. Zhang X., et al. “Prevalence of diabetic retinopathy in the United States, 2005-2008”. The Journal of the American Medical Association 304.6 (2010): 649-656.
  36. Foley RN and Collins AJ. “The growing economic burden of diabetic kidney disease”. Current Diabetes Reports 9.6 (2009): 460-465.
  37. Rein DB., et al. “The economic burden of major adult visual disorders in the United States”. Archives of Ophthalmology 124.12 (2006): 1754-1760.
  38. Lu FP., et al. “Sex difference in the impact of diabetes on the risk of geriatric conditions”. Geriatrics and Gerontology International 13 (2013): 116-122.
  39. Jackson RA., et al. “Urinary incontinence in elderly women: findings from the Health, Aging, and Body Composition Study”. Obstetrics and Gynecology 104.2 (2004): 301-307.
  40. Lifford KL., et al. “Type 2 diabetes mellitus and risk of developing urinary incontinence”. Journal of the American Geriatrics Society 53.11 (2005): 1851-1857.
  41. Pijpers E., et al. “Older individuals with diabetes have an increased risk of recurrent falls: analysis of potential mediating factors: the Longitudinal Ageing Study Amsterdam”. Age Ageing 41.3 (2012): 358-365.
  42. Schwartz AV., et al. “Older women with diabetes have a higher risk of falls: a prospective study”. Diabetes Care 25.10 (2002): 1749-1754.
  43. Pijers E., et al. “Older individuals with diabetes have an increased risk of recurrent falls: analysis of potential mediating factor: The Longitudinal Ageing Study Amsterdam”. Age Ageing 41 (2012): 358-365.
  44. Feil DG., et al. “Risk of hypoglycemia in older veterans with dementia and cognitive impairment: implication for practice and policy”. Journal of the American Geriatrics Society 59 (2011): 2263-2272.
  45. Yaffe K., et al. “Association between hypoglycemia and dementia in a biracial cohort of older adult with diabetes mellitus”. The Journal of the American Medical Association 173 (2013): 1300-1306.
  46. Feil D and Unutzer J. “Cognitive impairment, chronic medical illness, and risk of mortality in an elderly cohort”. The American Journal of Geriatric Psychiatry 11 (2003): 551-560.
  47. Hajjar ER., et al. “Polypharmacy in elderly patients”. The American Journal of Geriatric Pharmacotherapy 5.4 (2007): 345-351.
Citation: Sharifa Salem Alshehri., et al. “Diabetes Complications among Elderly in Family Practice”. EC Microbiology 16.2 (2020): 01-07.

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