Research Article
Volume 18 Issue 6 - 2022
Antibiotic Susceptibility of Enterobacterales and Cocci Uropathogens in Patients Attending Regional Hospital of Dedougou, Western Region (Burkina Faso)

René Dembélé1,2*, Roger Sanou1, Oumar Traoré1,2, Nafissatou Ouédraogo1,2, Hiliassa Coulibaly1, Alix Bénédicte Kagambega1, Alassane Halawen Mohamed1, Frédéric François Bado1, Wendpoulomdé AD Kaboré1, Dramane Sanou3, Georgette Djiguemde-Nikiéma3, Issiaka Soulama4,5, Alfred S Traoré1 and Nicolas Barro1

1Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food/ 03 BP 7021 Ouagadougou 03, Burkina Faso
2University of Dedougou, BP 176 Dedougou, Burkina Faso
3Regional Hospital of Dedougou, Burkina Faso
4National Centre for Research and Training on Malaria (INSP/CNRFP), 01 BP 2208 Ouagadougou 01, Burkina Faso
5Research Institute for Health Sciences (CNRST/IRSS), 03 BP 7192 Ouagadougou 03, Burkina Faso
*Corresponding Author: René Dembélé, Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food/ 03 BP 7021 Ouagadougou 03, Burkina Faso.
Received: April 22, 2022; Published: May 24, 2022




Abstract

Making the diagnosis of urinary tract infection (UTI) and deciding when to initiate antimicrobial therapy remains a challenge to healthcare providers. This study was focused on the identification of bacterial pathogens causing UTI as well the evaluation of related antibiogram. A cross-sectional study was carried out over a period of one year (March 2018 to February 2019) in the Western part of Burkina Faso. In total, 388 urines samples were collected from individuals with suspected UTIs attending the Regional Hospital of Dedougou. Samples were inoculated on recommended media and isolation-identification of the bacterial strains were performed using standard microbiological protocols. Antibiotic susceptibility was carried out following European committee on antimicrobial susceptibility testing (EUCAST) recommended guidelines. The overall hospital prevalence of UTIs was 66% with 78.1% for males and 21.9% for females. In addition, half of the patients were under antibiotic treatment. Out of the 388 tested specimens, 132 (34.02%) had significant bacterial growth. Escherichia coli (44.7%) was the most frequently isolated specie and 56.8% of the strains were isolated from male patients. Enterobacterales were mainly resistant to amoxicillin-clavulanate, amoxicillin, ceftriaxone, ciprofloxacin and trimethoprim-sulfamethoxazole. Cocci isolates were resistance to oxacillin, norfloxacin and trimethoprim-sulfamethoxazole. At least, 17 of the Enterobacterales and 9 of the Cocci were multidrug resistant. The majority of isolates were resistant to commonly prescribed antibiotics. Therefore, the physician should strictly follow the culture report before starting therapy to prevent the emergence of multidrug resistance.

 

Keywords: Urinary Tract Infections; Uropathogens; Antibiotic Susceptibility; Multi-Drug Resistance; Burkina Faso

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Citation: René Dembélé., et al. “Antibiotic Susceptibility of Enterobacterales and Cocci Uropathogens in Patients Attending Regional Hospital of Dedougou, Western Region (Burkina Faso)”. EC Microbiology 18.6 (2022): 23-32.

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