Case Report
Volume 18 Issue 4 - 2022
Disseminated Cryptococcosis Caused by Cryptococcus albidus during HIV-AIDS and Literature Review
Kouakou Affoué Sandrine Josette1*, Kouabenan ASA2, Zika KD1, Karidioula YLC1, Gué IP2 and Adoubryn KD1
1Laboratory of Parasitology-Mycology, Medical School, Bouaké, Côte d’Ivoire
2Dermatology, Medical School, Bouaké, Côte d’Ivoire
*Corresponding Author: Kouakou Affoué Sandrine Josette, Laboratory of Parasitology-Mycology, Medical School, Bouaké, Côte d’Ivoire.
Received: October 11, 2021; Published: March 31, 2022


The aim of our study is to report at first the only case of disseminated cryptococcosis caused by Cryptococcus albidus during AIDS revealed by a skin involvement in Bouaké and then to present an exhaustive review of the literature making the inventory of the infection with Cryptococcus albidus in immunocompromised HIV subjects.

A 44-year-old HIV-positive patient consults for skin involvement suspected of skin cryptococcosis. Mycological examinations of skin biopsy fragments and the cerebro-spinal fluid extension assessment revealed disseminated cryptococcosis due to Cryptococcus albidus in a patient with deep cell immunosuppression with TCD4 lymphocytes at 21 cells/mm3. The patient died after 7 days of monotherapy with fluconazole.

From 1996 to 2020 only four cases of Cryptococcus albidus infections during AIDS were published. There are 3 cases of invasive infections including two fungemias, one meningitis and one case of localized eye infection. Our case occurred in 2019, 5 years after the last publication. All organs can be affected with a predilection for the central nervous system and blood. The treatment is identical to that of forms due to Cryptococcus neoformans.


Keywords: Disseminated Cryptococcosis; Skin Involvement; HIV-AIDS; Cryptococcus albidus; Fluconazole; Bouaké-Côte d’Ivoire



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Citation: Kouakou Affoué Sandrine Josette., et al. “Disseminated Cryptococcosis Caused by Cryptococcus albidus during HIV-AIDS and Literature Review”. EC Microbiology 18.4 (2022): 66-71.

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