Short Communication
Volume 17 Issue 3 - 2021
Short Letter about Genome Editing and Synthetic Virus
Mostafa G Fad*
PhD of Microbiology, Nuclear Material Authority, Egypt
*Corresponding Author: Mostafa G Fad, PhD of Microbiology, Nuclear Material Authority, Egypt.
Received: January 28, 2021; Published: February 27, 2021




Abbreviations

RNA: Ribonucleic Acid; DNA: Deoxyribonucleic Acid; COVID 19: Name given by WHO to the disease caused by the SARS-COV-2 (2019-Nco V) Virus

By 2002, three microbiologists reported the fake union of poliovirus, inciting universal shock and concern that other dangerous infections may moreover be made. A long time afterward, they see back on their work and examine morals, security and the longer term of manufactured science. Newer technology, DNA synthesis, has now give us the ability to write DNA It is clear that we presently have the innovation for building an engineered genome through DNA amalgamation or genome altering, the Manufactured genome basically had the same engineering and grouping as the wild sort strain and by phenotype investigation of the modern strain it was vague in appearance and development to the initial wild-type strain.

References

  1. , et al. “MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network”. Science 297.5583 (2000): 1016-1018.
  2. , et al. “Generating a synthetic genome by whole genome assembly: φX174 bacteriophage from synthetic oligonucleotides”. Proceedings of the National Academy of Sciences of the United States of America 100.26 (2003): 15440-15445.
  3. , et al. “Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome”. Science 319.5867 (2008): 1215-1220.
  4. , et al. “Creation of a bacterial cell controlled by a chemically synthesized genome”. Science 329.5987 (2010): 52-56.
  5. , et al. “Total Synthesis of a Functional Designer Eukaryotic Chromosome”. Science 344.6179 (2014): 55-58.
  6. , et al. “Rewriting the blueprint of life by synthetic genomics and genome engineering”. Genome Biology 16.125 (2015).
  7. Doudna and Charpentier. “CRISPER-Cas9 genome editing”. Science 346 (2014): 1258096.
  8. , et al. “Programming cells by multiplex genome engineering and accelerated evolution”. Nature 460.7257 (2009): 894-898.
  9. Po´sfaiet., et al. “Emergent properties of reduced-genome Escherichia coli”. Science 5776 (2006): 1044-1046.
  10. Jang YJ., et al. “Elimination of the cryptic plasmid in Leuconostoc citreum by CRISPR/Cas9 system”. Journal of Biotechnology 251 (2017): 151-155.
  11. Gabrielle Samuel., et al. “Back to the future: Controlling synthetic life science trade in DNA sequences”. Bulletin of the Atomic Scientists5 (2010): 9-20.
  12. James M Acton., et al. “Beyond the Dirty Bomb: Re-thinking Radiological Terror” (2007): 151-168.
Citation: Mostafa G Fad. “Short Letter about Genome Editing and Synthetic Virus”. EC Microbiology 17.3 (2021): 08-09.

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