Research Article
Volume 17 Issue 2 - 2021
Visual Outcome and Quality of Life after Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK)
Basil Alhusssin1*, Nourah Altuwaijri2, Rabia Bashir1, Shiji Gangadharan1, Albandary Alhamzah2 and Fahad Alfardan1
1King Abdulaziz Medical City, Riyadh, Saudi Arabia
2King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
*Corresponding Author: Basil Alhusssin, King Abdulaziz Medical City, Riyadh, Saudi Arabia..
Received: January 16, 2021; Published: January 20, 2021


Purpose: To evaluate the visual outcome and patient-related quality of life (QoL) after Descemets stripping automated endothelial keratoplasty (DSAEK).

Methods: Patients were enrolled if they had pseudophakic bullous keratopathy or Fuchs endothelial dystrophy and underwent DSAEK. Data were collected on patient demographics and best corrected visual acuity (BCVA) before and after DSAEK. Patients completed the National Eye Institute Visual Functioning Questionnaire - 39 (NEI VFQ-39) at least 1 year after DSAEK. Descriptive statistics are reported. The Student t-test was used to compare means between genders. A P value less than 0.05 was considered statistically significant.

Results: The study sample was comprised of 13 patients. Preoperatively, one eye had BCVA 20/100 and all other eyes had vision < 20/200. At last postoperative visit, BCVA improved by 2 or more lines in all eyes. The mean improvement in BCVA was 2.5 lines. Complications after DSAEK included rejection in 2 eyes for which DSAEK was repeated without further sequelae. The NEI VFQ-39 total score was 84.25 ± 18.96. The scores per subscales varied from 72.5 ± 21.38 for the “General health” subscale to 93.27 ± 10.66 for the “Dependency” subscale (Table 2). There were no statistically significant differences between genders for the different subscales (P < 0.05, all between-gender subscale comparisons).

Conclusion: A clinically significant increase in BCVA improved patient related quality of life.

Keywords: Quality of Life (QoL); Descemets Stripping Automated Endothelial Keratoplasty (DSAEK); Best Corrected Visual Acuity (BCVA)


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Citation: Basil Alhusssin., et al. “Visual Outcome and Quality of Life after Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK)”. EC Microbiology 17.2 (2021): 196-202.

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