Research Article
Volume 17 Issue 1 - 2021
The Association Between COVID-19 and Hypertension: A Literature Review
Sami Bilal1*, Mohmed Basalama2, Abdelrahman Raghamtalla3, Ziyad Alghofaili4, Abdullah Alburayh5, Mohammed Alqahtani6, Hamza Bukhari7, Ahmed Alobaidi8, Sara Albloushi9 and Samar Baloush10
1Consultant of Internal Medicine, Department of Internal Medicine, King Fahad Hospital, Jeddah, Saudi Arabia
2Internal Medicine Specialist, Department of Internal Medicine, King Fahad Hospital, Jeddah, Saudi Arabia
3Al Qunfudah Makhshush Primary Health Center, Ministry of Health, Al Qunfudah, Saudi Arabia
4College of Medicine, Imam Muhammad Ibn Saud Islamic University, Riyadh, Saudi Arabia
5College of Pharmacy, Qassim Univeristy, Qassim, Saudi Arabia
6College of Medicine, King Khalid University, Abha, Saudi Arabia
7College of Medicine, University of Jeddah, Jeddah, Saudi Arabia
8College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
9College of Medicine, Ibn Sina National College, Jeddah, Saudi Arabia
10College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
*Corresponding Author: Sami Bilal, Consultant of Internal Medicine, Department of Internal Medicine, King Fahad Hospital, Jeddah, Saudi Arabia.
Received: November 11, 2020; Published: December 31, 2020


Hypertension is a highly prevalent disorder and is estimated to affect at least one in every four individuals. Developing hypertension is mostly dependant on the patient’s lifestyle. It was reported among the comorbidities that were reported with the severity of COVID-19 infection. Reports showed that it is the commonest comorbidity that is associated with COVID-19 infection and severity. The prevalence of hypertension in COVID-19 patients is hugely variable and a rate of 15 - 35% has been reported by various investigations. Moreover, hypertensive patients are most prone to develop severe complications. The presence of hypertension and cardiovascular diseases were associated with increasing the risk of mortality by 2 - 3 times. Many reports estimated a significant association between hypertension and other comorbidities and mortality among COVID-19 patients. Additionally, the effect of hypertension is exaggerated when present with other co-morbidities as diabetes. Regarding the renin-angiotensin-aldosterone system (RAAS) inhibitors administration for controlling blood pressure in hypertensive COVID-19 patients, available data showed that no significant side effects were associated with these types of drugs. In fact, a previous report showed that RAAS inhibitors were significantly associated with reduced COVID-19 risks for developing severe disorders and death. Therefore, all theoretical approaches about the harmful effects of RAAS inhibitors when associated with COVID-19 infection should be ignored.

Keywords: Hypertension; COVID-19; Angiotensin; RAAS Inhibitors; Blood Pressure; Cardiovascular


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Citation: Sami Bilal., et al. “The Association Between COVID-19 and Hypertension: A Literature Review”. EC Microbiology 17.1 (2021): December 31.

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