Review Article
Volume 16 Issue 7 - 2020
Review on Thalassemia Epidemiology and Management in Children
Raniyah Embarak D Alharbi1*, Abdulaziz Hameed H Alluhaibi2, Zaki Ghali Alhothli2, Sara Faisal Alhassan2, Bayan Mohammed Almehmadi2, Shatha Abdulaziz Al Zaydi2, Raghdah Khamees Al Harbi3, Hamad Rasheed Alotaibi4 and Afnan Mohammed Al Gethami5
1Pediatric Intensivist in Hera General Hospital, Residents Training Programs Director, Head of Pediatric Critical Care Scientific Council, Mecca, Saudi Arabia
2Hera General Hospital, Mecca, Saudi Arabia
3King Abdulaziz Hospital, Saudi Arabia
4Shaqra University, Saudi Arabia
5Pediatric Resident, Taif Children Hospital, Taif, Saudi Arabia
*Corresponding Author: Raniyah Embarak D Alharbi, Pediatric Intensivist in Hera General Hospital, Residents Training Programs Director, Head of Pediatric Critical Care Scientific Council, Mecca, Saudi Arabia.
Received: June 08, 2020; Published: June 23, 2020




Abstract

Background: Thalassemia is a genetic disorder which involves the formation of abnormal hemoglobin. Thalassemia is autosomal recessive, meaning both parents must be affected with the disease or carriers for it to be passed to the next generation.

A patient with thalassemia not only has low levels of hemoglobin present in his or her bloodstream but also lacks good quality hemoglobin. Although some mild forms of thalassemia can even go unnoticed and cause only mild anemia and patients with iron deficiency problems, some more serious types of thalassemia can also lead to death.

Aim of the Study: This review aims to highlight epidemiology and management of thalassemia in Children.

Conclusion: Thalassemia has adverse effects for many organs and it has high morbidity without a cure. An interprofessional team that involves a thalassemia treatment manager, cardiologist, hepatologist, endocrinologist and psychologist may better treat the condition. Community treatment, health assistance and social service are also an important part of the management. Education of patients is crucial and participation of social workers, including a geneticist, is important. Preventive approaches in some parts of the world include prenatal screening, prohibitions on issuing marriage licenses to two individuals with the same disease. Screening of children and pregnant women visiting clinics is an important method to reduce morbidity of the disease. Finally, successful high school screening should be considered instead of premarital testing, as high school screening has been shown to be more effective in reducing the incidence of β-thalassemia.

Keywords: Thalassemia; Management of Thalassemia; Epidemiology of Thalassemia

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Citation: Raniyah Embarak D Alharbi., et al.. “Review on Thalassemia Epidemiology and Management in Children”. EC Microbiology 16.7 (2020): 66-71.

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