Research Article
Volume 9 Issue 7 - 2020
Receptor Status of Women with Uterine Fibroids and Adenomyosis
Gutikova LV*, Kukharchyk YV and Pavlovskaya MA
Grodno State Medical University, Grodno, Belarus
*Corresponding Author: Gutikova LV, Grodno State Medical University, Grodno, Belarus.
Received: April 14, 2020; Published: June 02, 2020


Based on these studies, it was found that in women with uterine fibroids, combined with adenomyosis, there is a pronounced endometrial dysfunction, manifested by a violation of secretory transformations, an increase in fibroblastic changes in stromal cells and its progressive fibrosis, damage to the surface epithelium of the endometrium, a decrease in the level of expression of progesterone receptors and an increase intensities of expression of estrogen receptors both in the nuclei of superficial epithelial cells and gland glandulocytes and in stromal cells. Due to impaired reproductive health in women with myoma uterus and adenomyosis. When choosing therapeutic measures, it is necessary to evaluate two conditions: the morphotype of the node and the presence of adenomyosis. Drug therapy should include the appointment of progestins or antiestrogen drugs.

Keywords: Uterine Fibroids; Adenomyosis; Estrogen Receptors; Progesterone Receptors


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Citation: Gutikova LV., et al. “Receptor Status of Women with Uterine Fibroids and Adenomyosis”. EC Gynaecology 9.7 (2020): 10-16.

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