Case Report
Volume 9 Issue 3 - 2020
Mammary Paget Disease with Pemphigus Like Apparence in Histology: A Case Report with the Literature Review
Khadija Elboukhari*, Kaoutar Achehboune, Sara Elloudi, Hanane Baybay and Fatima Zahra Mernissi
Department of Dermatology, University Hospital of Fez, Morocco
*Corresponding Author: Khadija Elboukhari, Department of Dermatology, University Hospital of Fez, Morocco.
Received: January 27, 2020; Published: February 25, 2020


The mammary Paget disease is an uncommon disorder of the nipple-areola area, it is an intraepithelial adenocarcinoma that is clinically confused with inflammatory or infectious skin disease, this entity is usually underlying a ductal carcinoma. The histology examination identifies Pagets cells infiltrating the epidermis without invasion. We report a case of a 65 years old single woman who presented a Mammary Paget disease with a pemphigus-like appearance on the histology examination. We will also discuss this pathology through a brief review of the literature.

Keywords: Mammary; Paget; Pemphigus-Like; Ductal Carcinoma


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  3. Apalla Z., et al. “Dermoscopic features of mammary Paget’s disease: a retrospective case‐control study by the International Dermoscopy Society”. The Journal of the European Academy of Dermatology and Venereology (2019): 15732. 
  4. Waldman RA., et al. “Skin diseases of the breast and nipple: benign and malignant tumors”. Journal of the American Academy of Dermatology 80 (2019): 1467-1481.
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  9. Chaudary MA., et al. “Paget’s disease of the nipple: a ten year review including clinical, pathological and immunohistochemical findings”. Breast Cancer Research and Treatment 8.2 (1986): 139-146.
  10. Broecker JS., et al. “An atypical presentation of Paget’s Disease of the breast without nipple involvement: Case report and review of the literature”. Pathology - Research and Practice 213 (2017): 1454-1456. 
  11. Lallas A., et al. “Dermoscopy in general dermatology”. Dermatologic Clinics 31 (2013): 679-694.
  12. Guitera, P., et al. “Reflectance confocal microscopy for diagnosis of mammary and extramammary Paget’s disease”. The Journal of the European Academy of Dermatology and Venereology 27 (2013): e24-e29. 
  13. Yao Y., et al. “Breast-Conserving Surgery in Patients With Mammary Paget’s Disease”. Journal of Surgical Research 241 (2019): 178-187. 
  14. Ooi PS., et al. “Mammary Paget’s Disease of the Nipple: Relatively Common but Still Unknown to Many”. Journal of the Korean Academy of Family Medicine (2018). 
Citation: Khadija Elboukhari., et al. “Mammary Paget Disease with Pemphigus Like Apparence in Histology: A Case Report with the Literature Review”. EC Gynaecology 9.3 (2020): 01-05.

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