Case Report
Volume 7 Issue 3 - 2020
Giant Mesenteric Fibromatosis Associated with Non-Hodgkin Lymphoma. A Case Report and Literature Review
N Pujol-Cano1*, A Bianchi1, A Pagan-Pomar1, R Ramos-Asensio2, MA Martínez-Ortega2, JA Martinez-Corcoles1 and XF Gonzalez-Argente1
1Department of General Surgery, Hospital Universitario Son Espases, Palma de Mallorca, Spain
2Department of Pathological Anatomy, Hospital Universitario Son Espases, Palma de Mallorca, Spain
*Corresponding Author: N Pujol-Cano, Department of General Surgery, Hospital Universitario Son Espases, Palma de Mallorca, Spain.
Received: December 18, 2019; Published: February 28, 2020


Background: Mesenteric fibromatosis are benign locally-aggressive mesenchymal neoplasms that lack the potential for metastasis. They are related to Gardner’s Syndrome, previous trauma, abdominal surgery and prolonged intake of oestrogen. Differential diagnosis from similar tumours is crucial in order to establish the appropriate treatment and immunohistochemical features can only do the definitive diagnosis. Although medical therapies have a role for the treatment of mesenteric fibromatosis, surgical resection is the gold-standard procedure.

Methods: We are discussing about a 40-year-old male presented with a concomitant diagnosis of non- Hodking lymphoma and mesenteric fibromatosis not associated with any of the risk factors mentioned above. CT and PET scan are performed visualizing a vascularized and well-defined mesenteric center- abdominal solid mass with hypermetabolism contacting with the gastric body, the duodenum, the body and the tail of the pancreas, the transverse colon and the spleen. Ultrasound-guided trucut biopsy showed features suggestive of mesenteric fibromatosis.

Results: Elective laparotomy was done and a giant mass arising from mesentery was excised including partial gastrectomy and segmental resection of the transverse colon. Distal pancreatectomy, small bowel resection and successive splenectomy are performed due to a large hypertensive component. Postoperative period was uneventful. The histopathology of the surgical pieces is compatible with intra-abdominal desmoid fibromatosis.

Conclusion: As far as we know, it is the biggest case of mesenteric fibromatosis tumour excision reported in the literature. We also noticed that our case is the first reported case of concomitant presence of mesenteric fibromatosis and non-Hodgkin's lymphoma that has not relation to any described risk factor. More research is needed to establish what type of association this presentation may indicate.

Keywords: Mesenteric Fibromatosis; Desmoid Tumours; Non-Hodking Lymphoma


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Citation: N Pujol-Cano., et al. “Giant Mesenteric Fibromatosis Associated with Non-Hodgkin Lymphoma. A Case Report and Literature Review”. EC Gastroenterology and Digestive System 7.3 (2020): 01-10.

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