Research Article
Volume 8 Issue 10 - 2021
Acute Mesenteric Ischemia as a Complication of Chronic Psoriasis, a Rare Pathogenesis
Mirza Faraz Saeed1*, Sana Osama Al-Rawi2, Lina Osama Al-Rawi2, Sara Salah Khairi3 and Isam Mazin Juma4
1Specialist General and Colorectal Surgery, King Hamad University Hospital, Bahrain
2Intern, King Hamad University Hospital, Bahrain
3SHO, General Surgery, King Hamad University Hospital, Bahrain
4Consultant General and Colorectal Surgeon, King Hamad University Hospital, Bahrain
*Corresponding Author: Mirza Faraz Saeed, Specialist General and Colorectal Surgery, King Hamad University Hospital, Bahrain.
Received: July 29, 2021; Published: September 28, 2021


Background: Psoriasis is an autoimmune inflammatory dermatological disease that can have serious complications. Acute mesenteric ischemia is a rare complication that can present in cases of chronic psoriasis in which the blood supply to the superior mesenteric artery and the celiac trunk can be obstructed resulting in ischemia, bowel necrosis and can lead to gangrenous changes in multiple abdominal organs. In late diagnosis, this has a very poor prognosis and can lead to patient death.

Case Presentation: We report a case of a 49-year-old female who was a known case of psoriasis on medications. She presented with non-specific abdominal pain and vomiting for two days. CT scan showed occlusion of the celiac trunk and superior mesenteric artery with infarctions to multiple organs. She was diagnosed with mesenteric ischemia and underwent an exploratory laparotomy. Due to the late presentation, the patient quickly deteriorated and was put on end-of-life care.

Conclusion: Cases of AMI should be suspected in patients with chronic psoriasis who present with abdominal pain especially if there are other comorbidities that can predispose to thromboembolism. Early diagnosis and management can lead to better outcome.

Keywords: Acute Mesenteric Ischemia; Psoriasis; Acute Abdomen


  1. Griffiths CEM Barker JNWN. “Pathogenesis and clinical features of psoriasis”. Lancet9538 (2007): 263-271.
  2. Ryan C and Kirby B. “Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities”. Dermatologic Clinics1 (2015): 41-55.
  3. Rajiv Jain., et al. “Rare Case of Celiac Trunk and SMA Thrombosis Presenting as an Isolated Gangrenous Cholecystitis: A Surgical Surprise”. Journal of Evolution of Medical and Dental Sciences91 (2015): 15697-15699.
  4. Schoots IG., et al. “Systematic review of survival after acute mesenteric ischaemia according to disease aetiology”. British Journal of Surgery1 (2004): 17-27.
  5. Romano N., et al. “Acute thrombosis of the superior mesenteric artery in a 39-year-old woman with protein-S deficiency: a case report”. Journal of Medical Case Reports1 (2011): 17.
  6. Shapiro J., et al. “The association between psoriasis, diabetes mellitus, and atherosclerosis in Israel: a case-control study”. Journal of the American Academy of Dermatology4 (2007): 629-634.
  7. Ryan C and Kirby B. “Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities”. Dermatologic Clinics1 (2015): 41-55.
  8. Fan Z., et al. “Platelet dysfunction and its role in the pathogenesis of psoriasis”. Dermatology1 (2021): 56-65.
  9. Grozdev I., et al. “Psoriasis as a systemic disease”. Clinics in Dermatology3 (2014): 343-350.
  10. Keskin HA., et al. “Celiac artery thrombosis and superior mesenteric artery stenoses with essential thrombocythemia: a case report”. Case Reports in Medicine (2012): 741653.
  11. Hamza M., et al. “Mesenteric ischemia due to thrombosis involving the aorta, celiac artery, and superior mesenteric artery in a young female with protein C deficiency”. Cureus11 (2019): e6151.
  12. Mercogliano G., et al. “Gastric ischemia treated with superior mesenteric artery revascularization”. Clinical Gastroenterology and Hepatology4 (2007): A26.
  13. Mazzei MA. “Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery: a brief radiological commentary”. World Journal of Emergency Surgery 13 (2018): 34.
  14. Kirkpatrick IDC., et al. “Biphasic CT with mesenteric CT angiography in the evaluation of acute mesenteric ischemia: initial experience”. Radiology1 (2003): 91-98.
Citation: Mirza Faraz Saeed., et al. “Acute Mesenteric Ischemia as a Complication of Chronic Psoriasis, a Rare Pathogenesis”. EC Gastroenterology and Digestive System 8.10 (2021): 105-110.

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