Case Report
Volume 8 Issue 7 - 2021
Management of Intestinal Ischemia Secondary to Superior Venous Thrombosis: A Case Report
Zappalà Angelo*, Toscano Chiara, Schillaci Riccardo, Caruso Giovambattista and Reina Giuseppe Angelo
Department of General Surgery, Santissimo Salvatore Hospital District, Paternò, Italy
*Corresponding Author: Zappalà Angelo, Department of General Surgery, Santissimo Salvatore Hospital District, Paternò, Italy.
Received: May 03, 2021; Published: June 12, 2021


Introduction: Acute mesenteric venous thrombosis is a rare and potentially fatal condition with superior mesenteric vein being the most common site of thrombosis development. This potentially fatal condition results from a systemic hypercoagulable state “Virchow’s Triad” or abdominal infection draining into the portal venous system and often requires an emergency intestinal resection, with not rare postoperative complications.

Presentation of Case: We present a case of acute superior mesenteric venous thrombosis resulting in jejunal ischemia in a 64-year-old male with an history of cardiovascular and cerebrovascular diseases in family, was admitted to a local hospital, a few days of onset of diffuse abdominal pain. A computed tomography (CT) scan showed a massive thrombosis of the portal, splenic and inferior and superior mesenteric veins and their branches. On suspicion of an advanced intestinal infarction, we maked the decision to perform an emergency operation.

Discussion: We hope to emphasise that although radiology plays a crucial role in modern medicine, it is important to make therapeutic decisions based on clinical findings.

Conclusion: Acute mesenteric venous thrombosis has non-specific clinical characteristics can make an early diagnosis difficult. A multidisciplinary team approach to plan for the tailored treatment strategy suitable for each patient as all options are associated with significant risks.

Keywords: Intestinal Blockage; Gastrointestinal Radiology; Gastrointestinal Surgery; Intestinal Ischemia; Superior Mesenteric Vein Thrombosis


  1. Clavien PA., et al. “Venous mesenteric infarction: a particular entity”. British Journal of Surgery3 (1988): 252-255.
  2. Acosta S., et al. “Mesenteric venous thrombosis with transmural intestinal infarction: a population-based study”. Journal of Vascular Surgery1 (2005): 59-63.
  3. Grendell JH and Ockner RK. “Mesenteric venous thrombosis”. Gastroenterology2 (11982): 358-357.
  4. S Abu-Daff., et al. “Mesenteric venous thrombosis and factors associated with mortality: a statistical analysis with five-year follow-up”. The Journal of Gastrointestinal Surgery 13 (2009): 1245.
  5. AK Singal and PS Kamath. “Tefferi A: mesenteric venous thrombosis”. Mayo Clinic Proceedings 88 (2013): 285-294.
  6. Reinus JF., et al. “Ischemic diseases of the bowel”. Gastroenterology Clinics of North America – Journal2 (1990): 319-343.
  7. Abu-Laban RB., et al. “Acute mesenteric ischemia in a middle-aged patient: case report and discussion”. The Journal of Emergency Medicine6 (1995): 857-861.
  8. Golino A., et al. “Recurrent small bowel infarction associated with antithrombin deficiency”. The American Journal of Gastroenterology2 (1997): 323-325.
  9. Ozturk G., et al. “Acute mesenteric ischemia in young adults”. Wiener Medizinische Wochenschrift15-16 (2012): 349-353.
  10. OA Hatoum., et al. “Mesenteric venous thrombosis in inflammatory bowel disease”. Journal of Clinical Gastroenterology 39 (2005): 27-31.
  11. Demir IE., et al. “Beyond lactate: is there a role for serum lactate measurement in diagnosing acute mesenteric ischemia?” Digestive Surgery3 (2012): 226-235.
  12. Yikilmaz A., et al. “Value of multislice computed tomography in the diagnosis of acute mesenteric ischemia”. European Journal of Radiology2 (2011): 297-302.
  13. Barmase M., et al. “Role of multidetector CT angiography in the evaluation of suspected mesenteric ischemia”. European Journal of Radiology3 (2011): e582-587.
  14. Schieda N., et al. “Triphasic CT in the diagnosis of acute mesenteric ischaemia”. The European Radiology7 (2013): 1891-1900.
  15. Furukawa A., et al. “CT diagnosis of acute mesenteric ischemia from various causes”. American Journal of Roentgenology2 (2009): 408-416.
  16. Lee SS and Park SH. “Computed tomography evaluation of gastrointestinal bleeding and acute mesenteric ischemia”. Radiologic Clinics of North America1 (2013): 29-43.
  17. Cudnik MT., et al. “The diagnosis of acute mesenteric ischemia: A systematic review and meta-analysis”. Academic Emergency Medicine11 (2013): 1087-1100.
  18. Desai RK., et al. “CT evaluation of wall thickening in the alimentary tract”. Radiographics5 (1991): 771-783.
  19. Rajesh S., et al. “Imaging Diagnosis of Splanchnic Venous Thrombosis”. Gastroenterology Research and Practice (2015): 101029.
  20. Wiesner W., et al. “CT of acute bowel ischemia”. Radiology 3 (2003): 635-650.
  21. Lee KW and Choi YI. “Superior mesenteric vein thrombosis accompanied with severe appendicitis”. Korean Journal of Hepato-Biliary-Pancreatic Surgery 18 (2014): 101-103.
  22. Condat B., et al. “Recent portal or mesenteric venous thrombosis: increased recognition and frequent recanalization on anticoagulant therapy”. Hepatology 32 (2000): 466-470.
  23. Brandt LJ and Boley SJ. “AGA technical review on intestinalischemia. American Gastrointestinal Association”. Gastroenterology 118 (2000): 954-968.
  24. Malec L and Young G. “Treatment of venous thromboembolism in pediatric patients”. Frontiers in Pediatrics (2017): 5.
  25. Kumar R and Kerlin BA. “Thrombosis of the abdominal veins in childhood”. Frontiers in Pediatrics 5 (2017): 188-188.
  26. Singal AK., et al. “Mesenteric venous thrombosis”. Mayo Clinic Proceedings 88 (2013): 285-294.
  27. Guglielmi A., et al. “Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with ulcerative colitis: a case report”. World Journal of Gastroenterology 13 (2005): 2035-2038.
  28. Oldenburg WA., et al. “Acute mesenteric ischemia: a clinical review”. Archives of Internal Medicine 10 (2004): 1054-1062.
  29. Florim S., et al. “Acute mesenteric ischaemia: a pictorial review”. Insights Imaging 5 (2018): 673-682.
Citation: Zappalà Angelo., et al. “Management of Intestinal Ischemia Secondary to Superior Venous Thrombosis: A Case Report”. EC Gastroenterology and Digestive System 8.7 (2021): 36-41.

PubMed Indexed Article

EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005

EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777

EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347

EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478

EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253

EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033

EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992

EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505

EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793

EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211

EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047

EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560

EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318

EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819

EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840

EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344

EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476

EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658

EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489

EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278

EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108

EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571

EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333

EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883

EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001

EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937

EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723

EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726

EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603

EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646

EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616

EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290

EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226

EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812

EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268

News and Events

January Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the November issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before February 10, 2023.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.