Research Article
Volume 8 Issue 3 - 2021
Hepatic and Gastrointestinal Manifestation of COVID-19
Kamlesh Kumar Sharma1, Sudhir Maharshi2*, Shyam Sunder Sharma3, Bharat Sapra3 and Sandeep Nijhawan3
1Assistant Professor, Department of Gastroenterology, SMS Medical College and Hospitals, Jaipur, India
2Associate Professor, Department of Gastroenterology, SMS Medical College and Hospitals, Jaipur, India
3Senior Professor, Department of Gastroenterology, SMS Medical College and Hospitals, Jaipur, India
*Corresponding Author: Sudhir Maharshi, Assistant Professor, Department of Gastroenterology, SMS Medical College and Hospitals, Jaipur, India.
Received: December 31, 2020; Published: February 10, 2021




Abstract

Coronavirus disease of 2019 (COVID-19) is a disease resultant of a novel coronavirus, severe acute respiratory syndrome coronavirus 2. It emerged at the end of 2019 and spread almost in all the countries. Because of high infectivity rate, it was declared as pandemic in March 2020. The leading method of spreading is through airway droplets with a median incubation period is 5.1 days. Spectrum of illness varies from mild to severe with majority suffering with mild symptoms. Coronavirus disease of 2019 involves mainly the respiratory system but other organs like heart, kidney, liver, intestine may also be affected. Major hepatic and gastrointestinal manifestations include elevation of liver enzymes, nausea, vomiting and diarrhoea. Pathophysiology of these symptoms is explained by presence of the ACE-2 receptors in the biliary tree and intestinal mucosa. This virus has been isolated from the stool specimens of COVID-19 patients. Based on its disease extent and involvement of hepatic and gastrointestinal systems, COVID-19 poses a high risk for gastroenterologist and precautions during endoscopic procedures are required.

Keywords: SARS-CoV-2; COVID 19; Pandemic; Gastrointestinal; Manifestation

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Citation: Sudhir Maharshi., et al. “Hepatic and Gastrointestinal Manifestation of COVID-19”. EC Gastroenterology and Digestive System 8.3 (2021): 69-77.

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