Research Article
Volume 8 Issue 2 - 2021
Study of the Annual Costs Associated with the Treatment of Complex Refractory Perianal Fistulas in Patients with Crohn’s Disease
Martín-Arranz1*, I Pascual Migueláñez2 and JL Marijuán2
1Gastroenterology Department, Innate Immunity Group, IdiPAZ Institute for Health Research, Associate professor of Medicine in UAM. La Paz Hospital, Madrid, Spain
2General Surgery Department, HU. La Paz, Madrid, Spain
*Corresponding Author: Martín-Arranz, Gastroenterology Deparment, Innate Immunity Group, IdiPAZ Institute for Health Research, Associate professor of Medicine in UAM. La Paz Hospital, Madrid, Spain.
Received: December 03, 2020; Published: January 20, 2021




Abstract

The objective of this study is to quantify the economic impact of the treatment of Complex Perianal Fistulas (CPF) refractory to prior surgical or biological treatment in adult patients with Crohn's Disease (CD). After analysing the patient care pathway and the different treatment alternatives available, an economic model has been developed to allow for the cost estimation of the current approach to the treatment of refractory CPF in CD. In addition to the costs of each therapeutic approach, this model takes into account costs associated to disease recurrence, primary side-effects, and the impact of the disease on labour. Results of this model indicate that the estimated direct annual cost for the treatment of refractory CPF in CD is, at least, €15,241 per patient, amounting to € 21,253,374 for the total population in Spain, with an estimation of 1,395 patients. Regarding indirect costs, the impact on labour of the interventions, measured as the losses incurred as a consequence of sick leaves is estimated to be of at least €186,266 per year for the estimated population. Work absenteeism is estimated to amount to between 10 and 30 days for almost 70% of patients, incurring a total estimated annual cost of €804,599.

Keywords: Perianal Crohn´s Disease; Complex Fistulas; Costs; Healthcare Resources

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Citation: Martín-Arranz., et al. “Study of the Annual Costs Associated with the Treatment of Complex Refractory Perianal Fistulas in Patients with Crohn’s Disease”. EC Gastroenterology and Digestive System 8.2 (2021): 44-53.

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