Research Article
Volume 8 Issue 2 - 2021
Application of Belarusian-Made Self-Expanding Ti-Ni Stents in the Treatment of Obstructing Colorectal Cancer
VL Denisenko1,6* YМ Gain2, VV Rubanik3,4, EV Denisenko6, VV Rubanik Jr3,4, АV Erushevich5, GМ Shappo6, EI Veremei7 and VА Jurba7
1Vitebsk Regional Clinical Specialized Centre, Belarus
2The Belarusian Medical Academy of Postgraduate Education, Minsk, Belarus<
3The Institute of Technical Acoustics of the National Academy of Sciences of Belarus, Belarus
4Vitebsk State Technological University, Belarus
5Vitebsk Regional Clinical Oncological Centre, Belarus
6Vitebsk State Medical University, Belarus
7Vitebsk State Academy of Veterinary Medicine, Vitebsk, Belarus
*Corresponding Author: VL Denisenko, Vitebsk Regional Clinical Specialized Centre, Belarus.
Received: March 09, 2020; Published: January 18, 2021


Introduction: A Belarusian-made self-expanding titanium nickelide stent has been successfully used in the treatment of patients with obstructing colorectal cancer.

The Purpose of the Study: The study aims at determining the effectiveness of Belarusian-made stents in the treatment of patients with obstructing colorectal cancer.

Materials and Methods: Under the Import Substitution Programme, Belarusian researchers (the Joint Laboratory of Advanced Materials and Technologies of the Institute of Technical Acoustics of the National Academy of Sciences of Belarus and Vitebsk State Technological University) and employees of Vitebsk Regional Clinical Specialized Centre, Vitebsk Regional Clinical Oncological Centre and the Belarusian Medical Academy of Postgraduate Education developed a technology for manufacturing self-expanding titanium nickelide colonic stents that are designed to serve as a wire frame for holding open the bowel lumen and for further stenting of the narrowing when inserted into the narrowed part of the tumor. These stents successfully underwent all preclinical studies. Their clinical trial was conducted at Vitebsk Regional Clinical Specialized Centre where they were used for symptomatic treatment of a patient presenting with complicated colorectal cancer.

Results and Discussion: Given that the estimated cost of the Belarusian-made product for medical purposes in case of its mass manufacturing would be lower than that of imported counterparts, the first application of a self-expanding titanium nickelide stent made by the Joint Laboratory of Advanced Materials and Technologies of the Institute of Technical Acoustics and Vitebsk State Technological University holds out a hope of successful implementation of the National Import Substitution Programme in this area.

Conclusion: The development of the first Belarusian self-expanding titanium nickelide colonic stent and its first successful clinical application in the setting of urgent surgery suggest that further implementation of minimally invasive surgery for colon stenotic lesions caused by malignancy is possible both with regard to temporary restoration of colonic patency (as a preparatory measure for radical intervention) and with regard to permanent colonic stenting in the tumor area (in order to improve the quality of life for patients with inoperable colonic disease).

Keywords: Stenting; Colorectal Cancer; Stent; Titanium Nickelide


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Citation: VL Denisenko.,et al. “Application of Belarusian-Made Self-Expanding Ti-Ni Stents in the Treatment of Obstructing Colorectal Cancer”. EC Gastroenterology and Digestive System 8.2 (2021): 07-19.

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