Research Article
Volume 7 Issue 11 - 2020
The Presentation of Mallory-Weiss Syndrome Secondary to Underlying Pathologies
Azhar Hussain1,2*, Jasndeep Kaler2, Elsa Tabrez3, Neha Ali4, Sheharyar Hussain5 and Shams Tabrez6
1Doctoral Candidate of HealthCare Administration, Franklin University, Ohio, USA
2Medical Student, Xavier University School of Medicine, Aruba
3Medical Student, American University of Integrative Sciences, Barbados
4Psychiatry Resident, Nassau University Medical Center, New York, USA
5Doctoral Candidate of Clinical Psychology, John Jay College of Criminal Justice, New York, USA
6Assistant Professor of Medicine and Board-Certified Gastroenterology and Hepatology at University of Central Florida, Florida, USA
*Corresponding Author: Azhar Hussain, Medical Student, Xavier University School of Medicine, Aruba.
Received: September 13, 2020; Published: October 15, 2020


Mallory-Wiess Syndrome (MWS) is one of the common causes of acute upper gastrointestinal (GI) bleeding, characterized by the presence of longitudinal superficial mucosal lacerations. The esophageal lacerations that are seen with MWS stem from forceful retching and vomiting. The increased intraabdominal pressure causes gastric contents to be forced into the esophagus. The force itself has been postulated as being the cause of the Mallory-Weiss tears. The most common precipitating factors are considered vomiting and retching in correlation with a history of excessive drinking or physical findings consistent with chronic alcohol abuse. While chronic alcohol abuse is a well-known precipitating factor, other conditions such as hyperemesis gravidarum, bulimia nervosa, scleroderma, gastrointestinal reflux disease, and chemotherapy induced hyperemesis can also lead to MWS. The diagnosis of MWS is suggested clinically by a typical history of hematemesis that is known to occur after one or more episodes non-bloody vomiting. Diagnosis is achieved via upper GI endoscopy visualizing the Mallory-Weiss tears within the esophageal membrane. If the patient is stable, medical intervention is unnecessary. In the event that the amount of blood vomited is extensive, supportive management may be required such as blood transfusion, electrocautery, balloon tamponade.

Keywords:Mallory-Weiss Syndrome; Upper Gastrointestinal Bleed; Hematemesis; Bulimia Nervosa; Hyperemesis Gravidarum; Portal Hypertension; Cirrhosis; Chemotherapy-Induced Hyperemesis; Anorexia Nervosa


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Citation: Azhar Hussain., et al. “The Presentation of Mallory-Weiss Syndrome Secondary to Underlying Pathologies”. EC Gastroenterology and Digestive System 7.11 (2020): 26-41.

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