Volume 5 Issue 9 - 2018
Alleviating Malnutrition through Cultivation and Domestication of Healthy Gut Microbiota
Rajesh N Gacche*
Professor, Department of Biotechnology, Savitribai Phule Pune University, Pune, Maharashtra, India
*Corresponding Author: Rajesh N Gacche, Professor, Department of Biotechnology, Savitribai Phule Pune University, Pune, Maharashtra, India.
Received: August 08, 2018; Published: August 10, 2018
Citation: Rajesh N Gacche. “Alleviating Malnutrition through Cultivation and Domestication of Healthy Gut Microbiota”. EC Gastroenterology and Digestive System 5.9 (2018): 703-705.
Severe acute malnutrition is the world-leading cause of children mortality, its severity and incidence is more in majority of the developing countries most notably in sub-Saharan Africa, Central America and South Asia etc. The malnutrition driven mortality for children under 5 years of age accounts up to 1 - 6 million deaths every year [1]. Besides the remarkable progress made in the production of food grains, still we could not develop a concrete programme for tackling the global issue of malnutrition in many parts of the world. One of the reasons might be lack of information about the concrete players in causation of malnutrition. Perhaps, besides the involvement of inadequate nutrient intake along with additional environmental insults, there are few more players suspected to be instrumental in causation and progression of malnutrition. Our conventional thinking of correlating a poor diet as a major culprit of severe malnutrition is questioned on the eve of evolving findings that articulates the conspiracy of undomesticated bad microbiota in intestine in concert with nutrient poor diet promote and perpetuate malnutrition [2].
Sizable amount of research has accumulated in the recent past that describes the role of digestive tract beneficial bacteria in our overall health, carrying signals to our different organs, influencing our brain chemistry, and role in digestion of food that we eat. Of note, even though we are eating the most nutrient-rich diets consistently, but if we don’t have sufficient density of gut microbes needed to synthesize and absorb those nutrients from our food stuff, perhaps we might be victim of malnutrition. This clearly indicates that our gut microbes really make a difference in making us excited or depressed [3]. In the current state of the art, series of preclinical and clinical reports describes the link between gut microbiota and malnutrition. For example, it has been observed that microbiota assembly is found to be altered in children with undernutrition, resulting in persistent microbiota immaturity which is not rescued by currently used nutritional and dietary interventions.
Copyright: © 2018 Rajesh N Gacche. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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