Case Report
Volume 5 Issue 8 - 2018
Reverse Surgery (“Liver-First Approach”) for Hepatic Metastases from Breast Cancer: Case Report
Sergio Renato Pais-Costa1*, Rafael de Negreiros Botan1, Guilherme Crispim Costa2 and Sergio Luiz Melo Araújo2
1Hepatobiliopancreatic and Oncologist Surgeon at Hospital Brasília and University of Brasilia (UNB), Brasília, Federal District, Brazil
2General Surgeon at Brasília Hospital, Brasilia, Brazil
*Corresponding Author: Sergio Renato Pais-Costa, Hepatobiliopancreatic and Oncologist Surgeon at Hospital Brasília and University of Brasilia (UNB), Brasília, Federal District, Brazil.
Received: June 29, 2018; Published: July 31, 2018
Citation: Sergio Renato Pais-Costa., et al. “Reverse Surgery (“Liver-First Approach”) for Hepatic Metastases from Breast Cancer: Case Report”. EC Gastroenterology and Digestive System 5.8 (2018): 698-702.
Background: Hepatic resection for liver metastasis from breast cancer (LMBC) can lead to long-term survival. Since BC has been a very sensitive neoplasm to both chemotherapy and targeted therapy, surgical resection of residual LMBC after systemic therapy has presented an important role to attain long-term survival. Reverse approach (“liver-first approach”) has been performed for liver metastasis from colorectal cancer (LMCRC), especially to the multiple synchronic metastases that have presented partial response after systemic treatment.
Case Report: LMBC in young female who has undergone successful “liver-first approach” after partial response to systemic therapy. At first, she underwent open right hepatectomy with caudate lobectomy and atypical resection of three small lesions in left lobe. After two postoperative cycles of chemotherapy associated a target therapy, she has finally submitted a radical mastectomy and selective axillary lymphadenectomy. To date, thirty-two months after hepatic resection, she is alive without any recurrence.
Conclusion: Reverse approach for LMBC by means chemo-targeted therapy associated a HR may lead a long-term survival in selected cases as we have observed in this report. In fact, new studies must be performed to answer if this strategy can be validated.
Keywords: Breast Cancer; Hepatic Neoplasms/Surgery; Liver/Surgery; Hepatectomy
Copyright: © 2018 Sergio Renato Pais-Costa., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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