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Research Article
Volume 6 Issue 6 - 2021
Assessment of Serum Electrolytes in Subclinical Thyroid Disorders
Işılay Kalan Sarı1* and Muhammed Ali Coşkuner2
1Department of Endocrinology and Metabolic Disorders, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey
2Department of Internal Medicine, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey
*Corresponding Author: Işılay Kalan Sarı, Department of Endocrinology and Metabolic Disorders, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey.
Received: August 02, 2021; Published: September 07, 2021


Introduction and Aim: Thyroid hormones have different functions in the human body. They regulate body metabolism, body temperature, and electrolyte homeostasis. They regulate electrolyte balance by affecting renal blood flow, the glomerular filtration rate, and tubular function. Many studies investigating serum electrolytes in thyroid disorders are performed in subjects with overt hypothyroidism or hyperthyroidism. Our study aimed to investigate the effects of thyroid hormones on serum electrolytes in subclinical thyroid dysfunction.

Methods: We measured thyroid hormones and serum electrolytes in forty patients with subclinical hypothyroidism and forty patients with subclinical hyperthyroidism. We also evaluated age, sex, and body mass index-matched forty healthy controls.

Results: The potassium and phosphorus levels of the three groups were similar (p > 0.05). The mean calcium level was statistically significantly higher in the subclinical hyperthyroid group (9.7 ± 1.2 mg/dL) as compared to that in the subclinical hypothyroid group [(8.6 ± 2.6 mg/dL) p = 0.03] and healthy controls [(8.7 ± 2.1 mg/dL) p = 0.01]. The mean sodium was statistically significantly decreased in the subclinical hypothyroid group (128.4 ± 3.4 mg/dL) as compared to that in the subclinical hyperthyroid group [(140.9 ± 4.6 mg/dL) p < 0.001] and healthy controls [(138.3 ± 2.0 mg/dL) p < 0.001].

Conclusion: Our study suggests that even in subclinical states, thyroid disorders may affect serum electrolytes. Subclinical hypothyroid and hyperthyroid patients should be regularly checked for serum electrolytes.

Keywords: Subclinical Hypothyroidism; Subclinical Hyperthyroidism; Electrolytes


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Citation: Işılay Kalan Sarı and Muhammed Ali Coşkuner. “Assessment of Serum Electrolytes in Subclinical Thyroid Disorders”. EC Endocrinology and Metabolic Research 6.6 (2021): 28-32.

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