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Volume 6 Issue 3 - 2021
ISLET Neogenesis in Man Without the Need for Transplants
Claresa Levetan*
Fellow with Distinction, American College of Endocrinology, Diplomate, American Board of Internal Medicine, Diabetes, Endocrinology and Metabolism, Grand View Hospital, Pennsylvania, USA
*Corresponding Author: Claresa Levetan, Fellow with Distinction, American College of Endocrinology, Diplomate, American Board of Internal Medicine, Diabetes, Endocrinology and Metabolism, Grand View Hospital, Pennsylvania, USA.
Received: February 20, 2021; Published: February 27, 2021


This review demonstrates the role and the data supporting Reg gene peptides in forming new islet containing new populations of beta cells from one’s own progenitor cells in the pancreas. Data in man demonstrates that even those patients with 20 years of type 1 diabetes, can generate new islets with Reg gene peptides and during pregnancy when there is upregulation of REG genes. The distinctions between islets in mice and men are also described to provide an understanding of why, in man, there is a unique architecture and vascular of human islets requiring islets to function optimally within the pancreas..

Keywords: REG Gene; Reg (Protein); Reg Peptides; ISLET Neogenesis; Transplants


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Citation: Claresa Levetan. “ISLET Neogenesis in Man Without the Need for Transplants”. EC Endocrinology and Metabolic Research 6.3 (2021): 29-38.

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