Abstract
Background: Determining main predictors of prolonged intensive care unit (ICU) stay in patients undergoing heart valve surgeries is used to target high risk group to improve resource utilization and efficiency of ICU care and outcome. The present study aimed to assess clinical status of patients with rheumatologic valvular heart diseases who were candidate for valvular surgeries and also to determine main correlates of prolonged ICU stay in these patients.
Methods: The records of 688 patients with rheumatic heart diseases that underwent different types of heart valve surgeries at the Tehran Heart Center were retrospectively reviewed. The patients were assigned to two groups that experienced prolonged ICU stay (defined as the length of ICU stay longer than 6 days) or with ICU hospitalizations less than 6 days.
Results: The rate of prolonged ICU stay was found to be 10%. With respect to main determinants of prolonged ICU stay and using the stepwise logistic regression modeling, advanced age (OR = 1.237, p = 0.001), the presence of severe pulmonary insufficiency (OR = 3.168, p = 0.022), aortic stenosis (OR = 1.977, p = 0.021), history of brain stroke (OR = 2.410, p = 0.015), and tricuspid replacement procedure (OR = 8.047, p < 0.001) were main correlates of prolonged ICU stay. Moreover, atrial fibrillation correction could effectively shorten ICU stay (OR = 0.264, p = 0.012).
Conclusion: About 10% of patients undergo heart valve surgeries experience prolonged ICU stay that can be well predicted by some factors including advanced age, severe pulmonary insufficiency, aortic stenosis, brain stroke, and tricuspid replacement surgery. Atrial fibrillation correction may shorten ICU stay in these patients.
Keywords: Rheumatologic Valvular Heart Disease; Valvular Surgery; Intensive Care Unit; Prediction
References
- Maganti Kameswari., et al. "Valvular heart disease: diagnosis and management”. Mayo Clinic Proceedings5 (2010).
- Mohr Friedrich W. "Decade in review-valvular disease: Current perspectives on treatment of valvular heart disease”. Nature Reviews Cardiology11 (2014): 637-638.
- Sündermann Simon H., et al. "Indication and timing of heart valve surgery-summery of the European guidelines”. Praxis8 (2014): 445-451.
- Russell Elizabeth Anne., et al. "A review of valve surgery for rheumatic heart disease in Australia”. BMC Cardiovascular Disorders1 (2014): 134.
- Bernal José M., et al. "Surgery for rheumatic tricuspid valve disease: a 30-year experience”. The Journal of Thoracic and Cardiovascular Surgery2 (2008): 476-481.
- Mermel LA. "Infectious Disease Society of America; American College of Critical Care Medicine; Society for Healthcare Epidemiology of America. Guidelines for the management of intravascular catheter-related infections”. Clinical Infectious Diseases 32 (2001): 1249-1272.
- American Thoracic Society. "Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia”. American Journal of Respiratory and Critical Care Medicine 171 (2005): 388-416.
- Geerts William and Rita Selby. "Prevention of venous thromboembolism in the ICU”. Chest6 (2003): 357S-363S.
- Rimachi R., et al. "Survival and quality of life after prolonged intensive care unit stay”. Anaesthesia and Intensive Care1 (2007): 62-67.
- Timmers, Tim K., et al. "Long-term quality of life after surgical intensive care admission”. Archives of Surgery4 (2011): 412-418.
- Wang Chong., et al. "Risk model of prolonged intensive care unit stay in Chinese patients undergoing heart valve surgery”. Heart, Lung and Circulation11 (2012): 715-724.
- Cacciatore Francesco., et al. "Determinants of prolonged intensive care unit stay after cardiac surgery in the elderly”. Aging Clinical and Experimental Research6 (2012): 627-634.
- Xu Jianping., et al. "A preoperative and intraoperative predictive model of prolonged intensive care unit stay for valvular surgery”. The Journal of Heart Valve Disease2 (2006): 219-224.
- Saxena Akshat., et al. "Early and late outcomes after isolated aortic valve replacement in octogenarians: an Australasian Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database Study”. European Journal of Cardio-Thoracic Surgery1 (2012): 63-68.
- Daoud Emile G. "Management of atrial fibrillation in the post-cardiac surgery setting”. Cardiology Clinics1 (2004): 159.
- Lip Gregory YH and Hung-Fat Tse. "Management of atrial fibrillation”. The Lancet9587 (2007): 604-618.
- Sleeswijk Mengalvio E., et al. "Clinical review: treatment of new-onset atrial fibrillation in medical intensive care patients: a clinical framework”. Critical Care6 (2007): 233.
- Khoo Chee W and Gregory YH Lip. "Acute management of atrial fibrillation”. Chest3 (2009): 849-859.
- European Heart Rhythm Association. "Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)”. European Heart Journal 31 (2010): 2369-2429.
- Authors/Task Force Members., et al. "2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation Developed with the special contribution of the European Heart Rhythm Association”. European Heart Journal21 (2012): 2719-2747.
- Mathew Joseph P., et al. "A multicenter risk index for atrial fibrillation after cardiac surgery”. The Journal of the American Medical Association 14 (2004): 1720-1729.
- Auer Johann., et al. "Risk factors of postoperative atrial fibrillation after cardiac surgery”. Journal of Cardiac Surgery5 (2005): 425-431.
- Stewart Simon., et al. "A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up of the Renfrew/Paisley study”. The American Journal of Medicine5 (2002): 359-364.
- Moraca Robert J., et al. "Outcomes of tricuspid valve repair and replacement: a propensity analysis”. The Annals of Thoracic Surgery1 (2009): 83-89.
- Park Choung Kyu., et al. "Early and midterm outcomes for tricuspid valve surgery after left-sided valve surgery”. The Annals of Thoracic Surgery4 (2009): 1216-1223.
Journal Menu
PubMed Indexed Article
EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.
PMID: 31143884 [PubMed]
PMCID: PMC6536005
EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.
PMID: 31565701 [PubMed]
PMCID: PMC6764777
EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.
PMID: 27747317 [PubMed]
PMCID: PMC5065347
EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?
PMID: 31460519 [PubMed]
PMCID: PMC6711478
EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?
PMID: 30215059 [PubMed]
PMCID: PMC6133253
EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.
PMID: 30417173 [PubMed]
PMCID: PMC6226033
EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.
PMID: 30264037 [PubMed]
PMCID: PMC6155992
EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.
PMID: 30198026 [PubMed]
PMCID: PMC6124505
EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.
PMID: 30294723 [PubMed]
PMCID: PMC6169793
EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs
PMID: 29285526 [PubMed]
PMCID: PMC5743211
EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique
PMID: 29911204 [PubMed]
PMCID: PMC5999047
EC Microbiology
Macrophages and the Viral Dissemination Super Highway
PMID: 26949751 [PubMed]
PMCID: PMC4774560
EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.
PMID: 27390782 [PubMed]
PMCID: PMC4933318
EC Microbiology
Reactive Oxygen Species in HIV Infection
PMID: 28580453 [PubMed]
PMCID: PMC5450819
EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population
PMID: 26280024 [PubMed]
PMCID: PMC4533840
EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis
PMID: 28066845 [PubMed]
PMCID: PMC5214344
EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology
PMID: 28936490 [PubMed]
PMCID: PMC5604476
EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia
PMID: 28713879 [PubMed]
PMCID: PMC5510658
EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature
PMID: 28133641 [PubMed]
PMCID: PMC5267489
EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling
PMID: 29333536 [PubMed]
PMCID: PMC5766278
EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.
PMID: 31032493 [PubMed]
PMCID: PMC6483108
EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.
PMID: 30957099 [PubMed]
PMCID: PMC6448571
EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.
PMID: 30101228 [PubMed]
PMCID: PMC6086333
EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.
PMID: 31080964 [PubMed]
PMCID: PMC6508883
EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.
PMID: 31093608 [PubMed]
PMCID: PMC6513001
EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.
PMID: 31552397 [PubMed]
PMCID: PMC6758937
EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.
PMID: 31681909 [PubMed]
PMCID: PMC6824723
EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.
PMID: 31681910 [PubMed]
PMCID: PMC6824726
EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.
PMID: 31528859 [PubMed]
PMCID: PMC6746603
EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?
PMID: 31276119 [PubMed]
PMCID: PMC6604646
EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.
PMID: 31406965 [PubMed]
PMCID: PMC6690616
EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.
PMID: 31517314 [PubMed]
PMCID: PMC6741290
EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.
PMID: 31633124 [PubMed]
PMCID: PMC6800226
EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.
PMID: 29662969 [PubMed]
PMCID: PMC5898812
EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.
PMID: 30215058 [PubMed]
PMCID: PMC6133268
News and Events
March Issue Release
We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the March issue of respective journals and the latest articles can be viewed on the current issue pages.
Submission Deadline for Upcoming Issue
ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before April 07, 2023.
Certificate of Publication
ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.
Best Article of the Issue
Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.
Certifying for Review
ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.
Latest Articles
The latest articles will be updated immediately on the articles in press page of the respective journals.