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Editorial
Volume 5 Issue 12 - 2020
Cardiometabolic Diseases, Risk Stratification, and Management
Gundu HR Rao*
Emeritus Professor, Laboratory Medicine and Pathology, Director, Thrombosis Research, Lillehei Heart Institute, University of Minnesota, USA
*Corresponding Author: Gundu HR Rao, Emeritus Professor, Laboratory Medicine and Pathology, Director, Thrombosis Research, Lillehei Heart Institute, University of Minnesota, USA.
Received: October 26, 2020; Published: November 07, 2020




Cardiometabolic diseases such as hypertension, excess weight, obesity, type-2 diabetes, and vascular diseases have reached epidemic proportions worldwide [1-8]. Globally, an estimated 26% of the population of the World’s population (972 million) has hypertension. To achieve the global target to reduce the prevalence of hypertension by 25% by 2025, World Health Organization (WHO) and the United States Centers for Disease Control (CDC) and Prevention have launched the Global Hearts Initiative. With its technical package-HEARTS (manage cardiovascular diseases), MPOWER (control tobacco), Active (increased physical activity), SHAKE (reduce salt consumption) and REPLACE (eliminate trans-fat), the initiatives aim to improve heart health worldwide. Despite growing recognition of the problem, the obesity epidemic continues in the US at alarming rate. The prevalence of obesity currently is 40% among young adults aged 20 - 40 years, 45% among middle-aged adults aged 40 to 60 years, and 43% among adults aged 60 and older. Type-2 diabetes has become the biggest epidemic of this century worldwide. China and India lead the world, in terms of number of diabetic individuals. What really is baffling is the fact, that there are more prediabetics than diabetics. For instance, in the USA diabetic population is about 30 million. Whereas, according to the CDC, there are more than 100 million pre-diabetics. Diabetic population in China and India are close to 116 million and 80 million respectively. Worldwide prevalence of diabetes is estimated at 463 million and if we add pre-diabetics to this number, it would exceed a billion individuals. Cardiovascular diseases are the most common noncommunicable diseases globally, responsible for an estimated 18 million deaths in 2017, of which more than three quarters, were in low-income and middle-income countries.

References

  1. Hu C and Jia W. “Diabetes in China: Epidemiology and Genetic Risk Factors and Their Clinical Utility in Personalized Medicine”. Diabetes1 (2018): 3-11.
  2. Shen Xi., et al. “The Diabetic Epidemic in China: An Integrated Review of National Surveys”. Endocrine Practice 9 (2016): 1119-1129.
  3. Saeedi P., et al. “Global and regional diabetes prevalence estimates for 2019 and projections of 1030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition”. Lancet107843 (2019).
  4. Mills KT., et al. “Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-based Studies from 90 Countries”. Circulation6 (2016): 441-450.
  5. NCD Risk Factor Collaboration (NCD-RisC): Worldwide trends in body-mass index. Underweight, overweight, and obesity from 1975-2016: a pooled analysis of 2416 population-based measurements in 128.9 million children, adolescents and adults 390.10113 (2017): P2627-2642.
  6. Song P., et al. “Global and regional prevalence, burden and risk factors for carotid atherosclerosis: a systematic review, meta-analysis, and modeling study”. Lancet Global Health5 (2020): E721.E729.
  7. Roth GA., et al. “Global, regional, and national age-sex specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the 8). Global Burden of Disease Study 2017”. Lancet 392 (2018): 1736-1788.
  8. The WHO CVD Risk Chart Working Group. “World Health Organization Cardiovascular Disease Risk Charts: Revised Models to Estimate Risk in 21 Global Regions”. Lancet 7 (2019): E1332-E1345.
  9. Yusuf S., et al. “Effect of potentially modifiable risk factors associated with myocardial infraction in 52 countries (the INTERHEART study): a case-control study”. Lancet 364 (2004): 937-952.
  10. Di Cesare M., et al. “The contributions of risk factor trends to cardiometabolic mortality declines in 26 industrialized countries”. International Journal of Epidemiology 3 (2013): 838-848.
  11. Khera AV., et al. “Genetic risk, adherence to a healthy lifestyle, and coronary artery disease”. The New England Journal of Medicine 375 (2016): 2349-2358.
  12. O’Donnell MJ., et al. “Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case control-study”. Lancet 388 (2016): 761-765.
  13. Lopez-Jaramillo P., et al. “Epidemic of cardiometabolic diseases: A Latin American Point of View”. Therapeutic Advances in Cardiovascular Disease 2 (2011): 119-131.
  14. Gu D., et al. “Prevalence of cardiovascular disease risk factor clustering among the adult population of China: results from the International Collaborative Study of Cardiovascular Disease in Asia (Inter Asia)”. Circulation 112 (2005): 658-665.
  15. Rao GHR. “Coronavirus Disease (COVID-19) and Acute Vascular Events: Editorial”. Clinical and Applied Thrombosis/Hemostasis (2020): 26.
  16. Rao GHR. “Coronavirus (COVID-19), Comorbidities, and Acute Vascular Events; Guest Editorial”. EC Clinical Case Reports6 (2020): 87-91.
  17. Rao GHR. “Coronavirus Disease (Covid-19), Comorbidities, and Clinical Manifestations. Guest Editorial”. EC Diabetes and Metabolic Research 6 (2020): 27-33.
  18. Rao GHR. “Excess weight, Obesity, Diabetes and Coronavirus Disease”. Archives of Diabetes and Obesity 1 (2020).
  19. Chow JH., et al. “Aspirin us is associated with decreased mechanical ventilation, ICU admission and in-hospital mortality of hospitalized patients with COVID-10”. Journal of Anesthesia and Analgesia (2020).
  20. Cohn JN., et al. “Screening for early detection of cardiovascular disease in asymptomatic individuals”. American Heart Journal 4 (2003): 679-685.
  21. Rao GHR., et al. “Clinical Complications of Type-2 Diabetes Mellitus in South Asians and Chinese Populations: An Overview”. Diabetes and Metabolism 5 (2014): 420.
  22. Rao GHR. “Risk Prediction, Assessment, and Management of Type-2 Diabetes”. EC Endocrinology and Metabolic Research 1 (2018): 30-41.
  23. Malmefeldt E and Rao GHR: “Changing Concepts of Healthcare: Physical Activity, Fitness and Wellness”. EC Endocrinology and Metabolic Research 6 (2019): 238-250.
  24. Cohen JT., et al. “Does Preventive Care Save Money? Health Economics and the Presidential Candidates”. The New England Journal of Medicine 358 (2008): 661-663.
  25. Cutler DM and Summers LH. “The COVID-19 Pandemic and the $16 trillion virus”. The Journal of the American Medical Association 15 (2020): 1495-1496.
Citation: Gundu HR Rao. “Cardiometabolic Diseases, Risk Stratification, and Management”. EC Endocrinology and Metabolic Research 5.12 (2020): 01-04.

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