Metabolic diseases such as hypertension, excess weight, obesity, type-2 diabetes, and vascular diseases, have reached epidemic proportions worldwide [1-4]. These diseases contribute significantly, to the overall morbidity and mortality related to cardiovascular diseases and stroke. Vascular diseases have remained number one killers for over a century. Cardiovascular diseases are the most common noncommunicable diseases (NCDs) globally, responsible for an estimated 18 million deaths in 2017, of which more than three quarters were, in low-income and middle-income countries. Known metabolic risks, that promote the development of metabolic diseases include, oxidative stress, chronic inflammation, elevated blood pressure, insulin resistance, altered glucose and lipid metabolism, endothelial dysfunction and subclinical atherosclerosis. According to the experts, all these metabolic risks develop due to unhealthy diet, sedentary habits and poor lifestyle. Hence these diseases are called lifestyle disorders. Several studies have demonstrated that healthy diet, exercise and lifestyle changes, significantly reduce premature mortality due to vascular diseases [5-7]. However, no country has demonstrated reduction, or reversal of metabolic diseases. According to the then Director General, Dr. Margaret Chen, “As part of the 2030 Agenda for Sustainable Development Goals (SDGs), Member States have set an ambitious target, to reduce premature mortality from NCDs-including diabetes-by one third; achieve universal health coverage; and provide access to affordable essential medicines-all by 2030.

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