Short Communication
Volume 3 Issue 3 - 2018
Thyroid Disorders in Systemic Angiitis: Myth or Reality?
Department of Internal Medicine, Military Hospital of Gabes, Gabes, Tunisia
*Corresponding Author: Salem Bouomrani, Department of Internal Medicine, Military Hospital of Gabes, Gabes, Tunisia.
Received: July 24, 2018; Published: August 08, 2018
Citation: Salem Bouomrani. “Thyroid Disorders in Systemic Angiitis: Myth or Reality?”. EC Endocrinology and Metabolic Research 3.3 (2018): 133-135.
Thyroid disorders are among the most common endocrine pathologies and are often primary due to damage to the thyroid gland itself. Their overall prevalence is estimated at 10% and are largely dominated by subclinical or asymptomatic forms. This frequency is particularly
high in certain groups such as elderly people, pregnant women, people living in iodine deficient areas and those with a family history
of thyroid diseases [1].
Vasculitis or angiitis is an inflammation of the vascular wall that may be primitive defining primary vasculitis, or secondary to several factors/conditions (infections, toxic, solid neoplasia or malignant hemopathies, drug intake, connectivitis..) defining secondary vasculitis. The most appropriate nosological/nomenclature classification for vasculitis is that of the Chapel Hill consensus of 1994 revised in 2012
(International Chapel Hill Consensus Conference on the Nomenclature of Systemic Vasculitides (CHCC)) [2] based primarily on the caliber
and type of affected vessels. This classification distinguishes:
- - Vasculitis of large vessels: represented mainly by giant cell arteritis (GCA) or Horton’s disease and Takayasu’s disease (TD),
- - Vasculitis of medium-sized vessels: mainly represented by polyarteritis nodosa (PAN) and Kawasaki disease,
- - Vasculitis of small vessels: grouping vasculitis with antineutrophil cytoplasmic antibodies (ANCA), namely granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (GEPA) and microscopic polyangiitis (PAM), with cryoglobulinemic vasculitis, leukocytoclastic vasculitis and Henoch-Schonlein syndrome (HSS).
The 2012 revision of this consensus conference, recognized two new systemic diseases as vasculitis namely Behçet’s disease (BD) and Cogan’s syndrome. Both vasculitis affect all vessels independently of the type (artery or vein) and caliber (large, medium or small) [2].
Copyright: © 2018 Salem Bouomrani. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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