Short Communication
Volume 5 Issue 7 - 2021
C-ARDS, a Quick Approach
Jorge Hidalgo1*, Pedro Arriaga2, Fernando Cuellar3, Gerhaldine Morazan4 and Allyson Hidalgo5
1Professor of Critical Care, Head of the ICU and COVID-Unit at Belize Healthcare Partners, Belize
2Head of the Critical Care Unit, Karl Heusner Memorial Hospital, Belize
3Head of the Intensive Care Unit, Belize Medical Associates, Belize
4Medical Director, Central Medical Laboratory, Belize
5Biochemistry, Arizona State University, Phoenix, United States
*Corresponding Author: Jorge Hidalgo, Professor of Critical Care, Head of the ICU and COVID-Unit at Belize Healthcare Partners, Belize.
Received: June 04, 2021; Published: June 23, 2021




Abstract

Acute Respiratory Distress Syndrome (ARDS) defined as acute condition characterized by a diffused, inflammatory lung injury caused by increase pulmonary vascular permeability that induces inflammation and edema of the lungs. This process will result in changes in lung weight and loss of aerated lung tissue affecting lung compliance and the exchange of gases leading to hypoxemia [1,2].

In the case of COVID-19 pneumonia related ARDS (C-ARDS) there is also the presence of inflammation of the endothelium (endothelialitis) in the vascular system. This increases the risk for the development of thrombosis and in some cases the progression to pulmonary fibrosis [3-5].

References

  1. COVID-ICU Group for the R Network and the C-I Investigators. Clinical characteristics and day-90 outcomes of 4,244 critically ill adults with COVID-19: a prospective cohort study”. Intensive Care Medicine (2020): 1-14.
  2. Richards-Belle A., et al. “COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland”. Intensive Care Medicine11 (2020): 2035-2047.
  3. Dorward DA., et al. “Tissue-specific immmunopathology in fatal COVID-19”. American Journal of Respiratory and Critical Care Medicine2 (2021): 192-201.
  4. Patel BV., et al. “Pulmonary angiopathy in severe COVID-19: physiologic, imaging, and hematologic observations”. American Journal of Respiratory and Critical Care Medicine5 (2020): 690-699.
  5. Elinoff JM., et al. “The tumor lysis syndrome”. The New England Journal of Medicine 365 (2011): 571-572.
  6. M Ackermann., et al. “Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in covid-19”. The New England Journal of Medicine2 (2020): 120-128.
  7. PB Sherren., et al. “COVID-19-related organ dysfunction and management strategies on the intensive care unit: a narrative review”. British Journal of Anaesthesia6 (2020): 912-925.
  8. AJ Rodriguez-Morales., et al. “Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis”. Travel Medicine and Infectious Disease 34 (2020): 101623.
  9. R Da Rosa Mesquita., et al. “Clinical manifestations of COVID-19 in the general population: a systematic review (2020).
  10. G Grasselli., et al. “Baseline characteristics and outcomes of 1591 patients infected with SARS- CoV-2 admitted to ICUs of the Lombardy region, Italy”. The Journal of the American Medical Association16 (2020): 1574-1581.
  11. “Acute respiratory distress syndrome”. The New England Journal of Medicine 377 (2017): 1904-1905.
  12. “Acute respiratory distress syndrome: the Berlin Definition”. The Journal of the American Medical Association 307 (2012): 2526-2533.
  13. Bosmuller H., et al. “The pulmonary pathology of COVID-19 Virchows Archiv 478 (2021): 137-150.
  14. Hospital incidence and outcomes of the acute respiratory distress syndrome using the Kigali modification of the Berlin definition”. American Journal of Respiratory and Critical Care Medicine 193 (2016): 52-59.
  15. Menk M., et al. “Current and evolving standards of care for patients with ARDS”. Intensive Care Medicine 12 (2020): 2157-2167.
  16. Perchiazzi G., et al. “The use of positive end-expiratory pressure in patients affected by COVID-19: time to reconsider the relation between morphology and physiology”. Best Practice and Research: Clinical Anaesthesiology - Journal3 (2020): 561-567.
  17. Guérin C., et al. “Prone positioning in severe acute respiratory distress syndrome”. The New England Journal of Medicine 23 (2013): 2159-2168.
  18. Horby P., et al. “Dexamethasone in hospitalized patients with Covid-19 — preliminary report”. The New England Journal of Medicine (2020).
  19. Tang N., et al. “Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy”. Journal of Thrombosis and Haemostasis 5 (2020): 1094-1099.
  20. Olson G and Davis AM. “Diagnosis and treatment of adults with community-acquired pneumonia”. The Journal of the American Medical Association 9 (2020): 885.
  21. Tanzella G., et al. “Optimal approaches to preventing severe community-acquired pneumonia”. Expert Review of Respiratory Medicine 10 (2019): 1005-1018.
Citation: Jorge Hidalgo., et al. “C-ARDS, a Quick Approach”. EC Emergency Medicine and Critical Care 5.7 (2021): 50-54.

PubMed Indexed Article


EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005


EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777


EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347


EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478


EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253


EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033


EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992


EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505


EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793


EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211


EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047


EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560


EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318


EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819


EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840


EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344


EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476


EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658


EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489


EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278


EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108


EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571


EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333


EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883


EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001


EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937


EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723


EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726


EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603


EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646


EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616


EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290


EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226


EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812


EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268


News and Events


October Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the October issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

Ecronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before November 01, 2021.

Certificate of Publication

Ecronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

Ecronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.

Immediate Assistance

The prime motto of this team is to clarify all the queries without any delay or hesitation to avoid the inconvenience. For immediate assistance on your queries please don't hesitate to drop an email to editor@ecronicon.uk