Case Report
Volume 5 Issue 7 - 2021
Pilot Study of the Efficacy and Safety of Humulus lupulus in the Treatment of Mild Anxiety
Oliva Alfonso Isabel1*, Monleón Getino Antonio2, Olmo Quintana Vicente3, Oteiza Larrechea Laura4, Rodriguez Gomez Sandra4, Garromendiola Garay Jon Kepa4, Villa Basterretxea Maite5, Madrigal Hormaechea Marisol5, Jaio Senra Iraide5, del Otero Sanz Laura6 and Martin Villodre Joan7
1Internal Medicine, PhD Student at the University of Pharmacy of Barcelona, Spain
2Genetic, Microbiology and Statistics Department, Biology Faculty, University of Barcelona, Spain
3Head of the Pharmacy Service of Family and Community Medicine of Gran Canaria, Canary Government Health Department, Vice-President of the Ethical Committee Research with Medicine Hospital Dr. Negrín Gran Canaria (CEI/CEIm), Corresponding Academician Royal Academy of Medicine of the Canary Islands, Spain
4Family and Community Medicine, Osakidetza, Basque Government Health Department, Spain
5Family and Community Nursing, Osakidetza, Basque Government Health Department, Spain
6Preventive Medicine and Public Health, Melilla Government Delegation, Spain
7Biology, Health and Environment Department, University of Pharmacy of Barcelona, Spain
*Corresponding Author: Oliva Alfonso Isabel, Internal Medicine, PhD Student at the University of Pharmacy of Barcelona, Spain.
Received: February 27, 2021; Published: June 21, 2021


The ongoing coronavirus (COVID-19) pandemic is causing multiple psychiatric problems in several groups of the population, calling for the development of new approaches to manage these concomitant syndromes. After an in-depth review of the scientific literature of the European Medication Agency, it was observed that 14 plant species of the 408 (3%) documented by the Department of Environment and Territorial Policy of the Basque Government are approved for treatment of different pathologies at a European level. Among them, Humulus lupulus was selected for investigation as a medicinal plant with therapeutic application for anxiety. We plan to study the efficacy and safety of the plant by means of a randomized multicenter open clinical trial. Two treatment groups will be assessed in parallel: a group treated with the medicinal plant and another group receiving conventional treatment. The objective of the clinical trial is to describe the therapeutic effects of the medicinal plant H. lupulus administered in clinical practice in primary care, and to analyze its side effects and safety.

Keywords: Humulus lupulus; Anxiety; Medicinal Plants; Hops; COVID-19


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Citation: Oliva Alfonso Isabel., et al. “Pilot Study of the Efficacy and Safety of Humulus lupulus in the Treatment of Mild Anxiety”. EC Emergency Medicine and Critical Care 5.7 (2021): 09-17.

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