Research Article
Volume 5 Issue 3 - 2021
Antimicrobial Effects of Bryophyllum pinnatum and Garcinia kola Juice against Selected Uropathogens
Nweke Nicholas Simeon1*, Amala Smart Enoch1 and Aaron Umasoye Udogadi2
1Department of Medical Laboratory Science, Rivers State University, Nkpolu-Port Harcourt, Nigeria
2Department of Medical Microbiology and Parasitology, College of Health Sciences, University of Port Harcourt, Nigeria
*Corresponding Author: Nweke Nicholas Simeon, Department of Medical Laboratory Science, Rivers State University, Nkpolu-Port Harcourt, Nigeria.
Received: November 12, 2020; Published: February 27, 2021




Abstract

This study was aimed at determining the antimicrobial activities of Garcinia kola and Bryophyllum pinnatum juices on some selected uropathogens. The antimicrobial activities of the individual juice were tested and the synergistic activities of the combined neat juices of Garcinia kola and Bryophyllum pinnatum. The dilutions of the juices at concentrations of 75%, 50%, 25% and 10% were tested to determine their antimicrobial activities on the selected organisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus and Candida albicans. Agar well diffusion method was used on Muller-Hinton agar to check the susceptibility pattern. The juice of Garcinia kola showed the large zone of inhibition on E. coli with zone diameter of 22 mm at 100% concentration (neat), Garcinia kola was moderately sensitive to K. pneumoniae, P. mirabilis and C. albicans at the concentrations of 100% (neat) and 75%. S. aureus was resistance to Garcinia kola juice at all concentrations. Bryophyllum pinnatum showed antimicrobial activity against E. coli, K. pneumoniae, P. mirabilis, S. aureus but Candida albicans was resistant to it. The combination of Bryophyllum pinnatum and Garcinia kola juices showed some remarkable synergistic activities compared to when the juices were used individually. Staphylococcus aureus which was resistant to Garcinia kola and Candida albicans that was resistant to Bryophyllum pinnatum juice became susceptible to their combined juices at the concentrations of 75% and 100%.

Keywords: Antimicrobial Activity; Garcinia kola; Bryophyllum pinnatum; Juice; Uropathogens

References

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Citation: Nweke Nicholas Simeon., et al. “Antimicrobial Effects of Bryophyllum pinnatum and Garcinia kola Juice against Selected Uropathogens". EC Emergency Medicine and Critical Care 5.3 (2021): 01-06.

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