Research Article
Volume 4 Issue 10 - 2020
Can Exosome based Therapy Reduces the Severity of COVID-19?
Swatilekha Das*
School of Biotechnology, KIIT University, Bhubaneswar, India
*Corresponding Author: Swatilekha Das, School of Biotechnology, KIIT University, Bhubaneswar, India.
Received: August 31, 2020; Published: September 19, 2020


In the last twenty years, several viral epidemics such as severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) has been recorded [1]. In recent times unexplained cases with low respiratory infections detected in Wuhan, China, and poses a big challenge for the whole world [1]. WHO (World Health Organization) formally named this disease as COVID-19 (Corona Virus disease 2019), which is later named by the International Committee on the taxonomy of virus as SARS-CoV-2. Wuhan isolated SARS-CoV-2 belongs to the Sarbecovirus subgenus and Betacoronavirus genus [2]. This virus has been spreading around the world widely. This raises an urgent need for an effective therapeutic approach. Recently different medicines and a combination of drugs have shown promising results. Many companies and researchers are working on finding a suitable vaccine or proper medication for COVID-19. In this review, we aim to provide basic structural information about COVID-19 and possible target to check the growth of these viruses by using exosome-based CRISPR/cas13d technology. Exosome incorporated CRISPR/Cas13d based system may specifically target viral ORF1ab and S RNA of COVID19 to knock down the ability to reproduce. This promising method needs proper investigation and if proven effective that will be an excellent development to fight against the COVID19 pandemic.

Keywords: Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV); Middle East Respiratory Syndrome Coronavirus (MERS-CoV); COVID-19 (Corona Virus Disease 2019)


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Citation: Swatilekha Das. “Can Exosome based Therapy Reduces the Severity of COVID-19?”. EC Dental Science 19.10 (2020): 44-50.

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