Mini Review
Volume 4 Issue 8 - 2020
How Prion Particles are Lethal to Us?
Mohammad Salim1*, Mohammad Shahid Masroor2, Shagufta Parween3 and Aruna Singh1
1Sanjay Gandhi Smriti Govt. Autonomous P.G. College, Sidhi, A.P.S. University, Rewa, Madhya Pradesh, India
2People’s College of Dental Sciences and Research Center, People’s University, Bhopal, Madhya Pradesh, India
3All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India
*Corresponding Author: Mohammad Salim, Sanjay Gandhi Smriti Govt. Autonomous P.G. College, Sidhi, A.P.S. University, Rewa, Madhya Pradesh, India.
Received: June 25, 2020; Published: July 15, 2020


Stanely B. Prussiner got Nobel prize in 1997 for the discovery of prion particles composed of only misfolded proteins which are devoid of any genetic materials. These are responsible to cause several life threatening neurodegenerative and brain diseases like bovine spongiform encephalopathy (BSE) and Creutzfeldt Jacob disease (CJD) in animals and humans respectively. Currently, it has also been noticed that these prion particles are able to cause cancer. The present paper is an attempt to summarize the recent informations on prions developing cancer in human..

Keywords: Prions; Neurodegenerative Diseases; Cancer


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Citation: Mohammad Salim., et al. “How Prion Particles are Lethal to Us?”. EC Emergency Medicine and Critical Care 4.8 (2020): 57-60.

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