Literature Review
Volume 4 Issue 6 - 2020
Using Vitamin C as Pre-Exposure Prophylaxis and Treatment to Strengthen the Immune System against COVID-19: A Review of Current Literature
Jonathan Lukusa Tshimwanga1*, Jacques Lukenze Tamuzi2, Nuru Kaddu Mgori3 and Jacques WA Nsenda Kamangu3
1Department of Disaster Management, Faculty of Agriculture and Natural Sciences, University of the Free State, South Africa
2Division of Epidemiology, Faculty of Medicine and Community Health, Stellenbosch University, South Africa
3Independent Researcher, Senior HIV Clinical Mentor, South Africa
*Corresponding Author: Jonathan L Tshimwanga, PhD Candidate, Department of Disaster Management, Faculty of Agriculture and Natural Sciences, University of the Free State, South Africa.
Received: March 20, 2020; Published: May 15, 2020




Abstract

The coronavirus 19 (COVID-19) is a life-threating disease of public health importance. It is caused by the outbreak of a new coronavirus, leading to community-acquired pneumonia, as well as respiratory and multiple organ failure. The disease has spread across the globe, affecting numerous health systems and illustrating the prevailing gap in preventive and curative measures against disease outbreak and severe acute respiratory syndrome (SARS). More than 209,839 confirmed cases have been documented and 8778 deaths have been recorded within the first three months of the emergence of the disease. The high case fatality rate is due to the lack of a curative treatment or availability of a proven vaccine against SARS-CoV-2. Moreover, it is anticipated that the discovery of effective interventions might take longer; meanwhile, the COVID-19 pandemic is skyrocketing.

It is therefore imperative for the use of cost-effective, preventive and readily available interventions to be implemented instantly to curb the disease morbidity and mortality rate - for example, the use of vitamin C against numerous forms of influenza.

Vitamin C has shown a potent antimicrobial property in reducing the pathogenicity of viruses. Previous studies have illustrated the role of vitamin C in the treatment of the severe acute respiratory syndrome (SARS) outbreak during 2002 and the Middle East respiratory syndrome (MERS) outbreak during 2012.

In addition, there is an ongoing randomised control trial study in the Republic of China on the consumption of high-dose vitamin C in the treatment of COVID-19. Based on its pharmacodynamic, vitamin C is an essential adjuvant in the treatment of viral pneumonia and is also a cost-effective measure which can be given while waiting to prevent and treat COVID-19. In contrast, there are a few studies that contradict the effectiveness of vitamin C versus the recovery against influenza viruses. More research is, therefore warranted in order to evaluate the contradicting roles of vitamin C in the management of viral respiratory illnesses.

In this literature review, the authors emphasise the role of vitamin C in preventive and curative measures during the management of COVID-19.

Keywords: COVID-19; SARS-Cov2; MERS-CoV; Vitamin C; Coronavirus; Immune System

References

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Citation: Jonathan L Tshimwanga., et al. “Using Vitamin C as Pre-Exposure Prophylaxis and Treatment to Strengthen the Immune System against COVID-19: A Review of Current Literature”. EC Emergency Medicine and Critical Care 4.6 (2020): 85-91.

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