Research Article
Volume 6 Issue 1 - 2022
Reproductive Hormone Abnormalities in Married Women of Child Bearing Ages Evaluated for Infertility in the Commercial City of Aba, Southeast Nigeria
Nkpozi MO1*, Kamanu CO2, Kamanu Chuks2and Ohiri JU3
1Department of Internal Medicine, Abia State University Teaching Hospital, ABSUTH, Aba, Nigeria
2Department of Obstetrics and Gynaecology, ABSUTH, Aba, Nigeria
3Department of Chemical Pathology, Federal Medical Centre, FMC, Owerri, Nigeria
*Corresponding Author: Nkpozi MO, Consultant Physician/Endocrinologist, Department of Internal Medicine, Abia State University Teaching Hospital, ABSUTH, Aba, Nigeria.
Received: July 03, 2022; Published: July 25, 2022




Abstract

Hormonal abnormalities, leading to disorders of ovulation, are recognized female risk factors in couple infertility. Other female causes of infertility include endometriosis, tubal diseases and unexplained causes which may occur singly or in combination. Because of the psychosocial importance attached to reproduction in the society, infertile couples usually present to fertility clinics for evaluation and treatment. The extent of reproductive hormonal abnormalities in married women of child bearing ages seeking fertility solutions in Aba, Southeast Nigeria is not known. This study, therefore, set out to bridge this gap in knowledge. This was a cross- sectional study in which 170 female patients presenting to the Fertility Clinic of the Department of Obstetrics and Gynaecology (O and G), Abia State University Teaching Hospital (ABSUTH), Aba for evaluation and treatment were consecutively recruited. This study lasted from January 1, 2021 to September 30, 2021. Relevant data obtained were analyzed using Statistical Package for Social Sciences (SPSS) version 23.0 software. A total of 170 women who met the inclusion criteria for the study were recruited among which 91.8% had abnormal reproductive hormonal profile. The commonest reproductive hormonal abnormalities noted were low progesterone levels, hyperprolactinaemia, high follicle stimulating hormone (FSH) and luteinizing hormone (LH) in 54.1%, 42.4%, 20.6% and 18.2% of the study participants respectively. Hyperprolactinaemia was not significantly related to age of the subjects. It is recommended that infertile women who do not have structural causes of female infertility be promptly evaluated for hormonal abnormalities and treated accordingly.

Keywords: Aba; Female Reproductive Hormones; Female Infertility; Hyperprolactinaemia; Low Progesterone Levels; Southeast Nigeria

References

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Citation: Nkpozi MO., et al. “Reproductive Hormone Abnormalities in Married Women of Child Bearing Ages Evaluated for Infertility in the Commercial City of Aba, Southeast Nigeria”. EC Diabetes and Metabolic Research 6.1 (2022): 33-37.

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