Research Article
Volume 4 Issue 12 - 2020
Alteration of C-Peptide and Prostate Specific Antigen on Diabetics in Owerri
Nnodim Johnkennedy1* and Nwaokoro Joakin Chidozie2
1Department of Medical Laboratory Science, Faculty of Health Science, Imo State University, Owerri, Nigeria
2Department of Public Health, Federal University of Technology, Owerri, Imo State, Nigeria
*Corresponding Author: Nnodim Johnkennedy, Department of Medical Laboratory Science, Faculty of Health Science, Imo State University, Owerri, Nigeria.
Received: October 27, 2020; Published: November 28, 2020


Aim: This study was done to evaluate the levels of C-peptide and prostate specific antigen (PSA) on diabetics in Owerri, Nigeria.

Materials and Methods: This study involving 250 diabetics whose ages ranges from forty five years and sixty years Also, two hundred and fifty normal individuals of the same age group were used as control. Blood sample of both groups that were on fasting were collected for the assessing of C-peptide and prostate specific antigen. The levels of C-peptide and prostate specific antigen were determined using enzyme immunoassay. Statistical analysis was done using Student t test.

Results: The concentration of C-peptide in diabetics was significantly decreased when compared with the non-diabetics (p < 0.05). In the same vein, there was significant reduction of prostate specific antigen in diabetes when compared with the non-diabetics (p < 0.05).

Conclusion: This probably indicate that those with diabetes could likely have reduction of C-peptide and prostate specific antigen levels which may be beneficial in monitoring diabetics. It can be inferred that there may be decreased risk of prostate cancer in diabetes.

Keywords: C-Peptide; Prostate Specific Antigen; Diabetes


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Citation: Nnodim Johnkennedy and Nwaokoro Joakin Chidozie. “Alteration of C-Peptide and Prostate Specific Antigen on Diabetics in Owerri”. EC Diabetes and Metabolic Research 4.12 (2020): 04-07.

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