Research Article
Volume 4 Issue 11 - 2020
Drug-Related Problems in Type 2 Diabetes Patients with Acute Hyperglycemia
Aliah Ayub1, Hasniza Zaman Huri1* and Shireene Ratna Vethakkan2
1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, Malaysia
2Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
*Corresponding Author: Hasniza Zaman Huri, Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, Malaysia.
Received: September 17, 2020; Published: October 31, 2020




Patients with type 2 diabetes mellitus (T2DM) and acute hyperglycemia are at risk of drug- related problem (DRPs) due to unstable haemodynamic system and multiple comorbidities that require them to take multiple medications. This retrospective study was conducted to assess the types of DRPs. The assessment of DRPs was based on Pharmaceutical Network Care Europe (PCNE) tool V5.01. Among the 239 cases of acute hyperglycemia, a total of 466 DRPs had been identified, an average of 2.66 ± 2.058 DRPs per patient. The most common DRPs encountered were potential drug-drug interactions (48.9%), drug choice problem (41.5%), dosing problem (28.2%) and adverse reaction (26.9%). Drug/dose selection (24.3%), others (13.8%) and patient/psychological factors (10.6%) were the most common causes contributing to DRPs. Therefore, early identification of risk of DRPs among T2DM patients with acute hyperglycemia may enhance the pharmacological treatment and reduce risk of mortality and morbidity.

Keywords: Type 2 Diabetes Mellitus (T2DM); Drug-Related Problem (DRPs); Pharmaceutical Network Care Europe (PCNE)

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Citation: Hasniza Zaman Huri., et al. “Drug-Related Problems in Type 2 Diabetes Patients with Acute Hyperglycemia”. EC Diabetes and Metabolic Research 4.11 (2020): 27-40.

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