Research Article
Volume 4 Issue 10 - 2020
Assessment of the Relationship between the Hematological Parameters Activity and Type 2 Diabetic Ketoacidosis in Intensive Care Unit
Muhammet Emin Naldan1*, Duygu Kara2, Havva Tuğba Kiper Yilmaz3, Faruk Yildiz3, Kenan Çadirci3 and Ayşe Çarlioğu3
1Anesthesia and Reanimation Department, Erzurum Region Training and Research Hospital, Erzurum, Turkey
2Anesthesia and Reanimation Department, Adnan Menderes University, Aydin, Turkey
3Internal Medicine Department, Erzurum Region Training and Research Hospital, Erzurum, Turkey
*Corresponding Author: Muhammet Emin Naldan, Anesthesia and Reanimation Department, Erzurum Region Training and Research Hospital, Erzurum, Turkey.
Received: July 24, 2020; Published: September 30, 2020


Objective: In the intensive care unit, we investigated the relationship between MPV (mean platelet volume), RDW (red cell width distribution), NLR (Neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio) markers to identify chronic inflammation between patients diagnosed with DKA, patients diagnosed with diabetes, and healthy volunteers.

Methods: Sixty-five patients with DM diagnosis were included in the study. Of these, 32 had DKA, 33 did not have any diabetes complications. Forty five completely healthy persons were included in the study. Healthy volunteers Group 1, Diabetes alone Group 2, DKA-recognized domains were defined as Group 3. The MPV, RDW, PLO, NLO values were obtained by performing a hemogram examination.

Results: The mean MPV of Group 1 was 6.6 ± 0.9 fl, Group 2 was 7.7 ± 0.7 and Group 3 was 8.6 ± 1.6. There was a significant difference between groups in terms of MPV (p < 0.001). Positive correlation between serum NLR and RDW, PCT, PLR, MPV, age, AST, ALT, Basophil, MCHC, MCV, Hgb, Wbc, Plt, Neutrophil values; There was a negative correlation between albumin, SPO2, HCO3, pH and GCS values. MPV values correlated with HCO3, GKS, RDW, SPO2, NLR and pH values.

Conclusion: Elevated levels of NLR, PLR, MPV and RDW in patients with DKA lying in intensive care unit ere potential showed the presence of the inflation and mortalities were increased in these patients.

Keywords: Diabetic Ketoacidosis; Hematological Parameters; ICU


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Citation: Muhammet Emin Naldan., et al. Assessment of the Relationship between the Hematological Parameters Activity and Type 2 Diabetic Ketoacidosis in Intensive Care Unit”. EC Diabetes and Metabolic Research 4.10 (2020): 31-40.

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