Research Article
Volume 4 Issue 9 - 2020
Evaluation of NT-PROBNP Levels in Egyptian Patients with Type 2 Diabet
Mona Sadek1, Hassan A Shora2*, Lamiaa Barakat3 and Naglaa El-liethy1
1Professor of Biochemistry, Faculty of Girls, Ain Shams University, Cairo, Egypt
2Senior Research Scientist, Head of Medicine and Diabetes Center, Port-Said University, Port-Said and Ismailia General Hospital, Egypt
3Professor and Chairman of Biochemistry Department, Faculty of Science, Port-Said University, Egypt
*Corresponding Author: Hassan A Shora, Senior Research Scientist, Head of Medicine and Diabetes Center, Port-Said University, Port-Said and Ismailia General Hospital, Egypt.
Received: July 16, 2020; Published: August 20, 2020


Background: The N-terminal pro brain natriuretic peptide (Nt-proBNP) is known to be associated with cardiac stress. This study aimed to assess Nt-proBNP levels in type 2 diabetic patients without overt cardiac complications and to evaluate it in patients with microvascular complications.

Methods: We evaluated the Nt-proBNP levels in the study population which was grouped as: group one, control healthy subjects and group 2, type two diabetic patients with and without microvascular complications.

Results: Patients with type 2 diabetes were shown to have higher Nt-proBNP levels than control subjects and patients with microvascular complications of type 2 diabetes were shown to have higher Nt-proBNP values than patients without microvascular complications.

Conclusion: Our study findings of elevated Nt-proBNP levels in type 2 diabetic patients without overt cardiac disease, suggesting that type 2 diabetes having some degree of cardiac strain, even if non clinically diagnosed and may be beneficial as screening method to guide selection of type 2 diabetic patients who need dedicated cardiac investigations.

Keywords: Type 2 Diabetes Mellitus; N-Terminal Brain Natriuretic Peptide; Microangiopathy


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Citation: Hassan A Shora., et al. “Evaluation of NT-PROBNP Levels in Egyptian Patients with Type 2 Diabetes". EC Diabetes and Metabolic Research 4.9 (2020): 20-27.

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