Research Article
Volume 4 Issue 6 - 2020
Path Directed towards a Stage when we almost Cure Type1 Diabetes Mellitus (T1dm) after a Century of Insulin Advent
Kulvinder Kochar Kaur1*, Gautam Allahbadia2 and Mandeep Singh3
1Scientific Director, DR Kulvinder Kaur Centre For Human Reproduction, Jalandhar, Punjab, India
2Scientific Director, Rotunda-A Centre for Human reproduction, Mumbai, India
3Consultant Neurologist, Swami Satyanand Hospital, Jalandhar, Punjab, India
*Corresponding Author: Kulvinder Kochar Kaur, Scientific Director, DR Kulvinder Kaur Centre For Human Reproduction, Jalandhar, Punjab, India.
Received: February 22, 2020; Published: May 30, 2020


Following the discovery of insulin lives of type 1 diabetes mellitus (T1DM) patients changed dramatically so that what was literally a death warning became a disease that could be controlled although still remaining a chronic disease, with insulin not curing the disease process, rather only its consequences i.e. blood sugars. Noticeably insulin does not achieve normoglycaemia. Despite maximum sophisticated, practically ‘near closed loops’ ways, glucose homeostasis does not get back to normal. Both short as well as long term complications are incurred by T1DM patients, with hypoglycaemic as well as hyperglycaemic events as well as long term effects of enhanced glycosylation of proteins resulting in eye, renal, central nervous system (CNS) as well as other complications. These sequelae are correlated with marked morbidity as well as mortality despite following aggressive insulin treatment. Practically a century after insulin discovery, we still battle with the hurdle of addressing disease process by itself, just to make the life of these patients better. Lot of work have been done to be able to totally arrest the autoimmune mechanism damaging the insulin synthesizing cells within the pancreas, or minimum at least reduce the speed of the process for blunting as well as delaying short as well as long term complications. Basic idea is to discuss a method that might aid in quantitative result measurements by particular therapies, short or clinical cure might be contrasted and exact advantage of their help in DM treatment might get assessed by the T1DM metabolic recovery index (DMMRI).

Keywords: T1DM; Autoimmune Process; Metabolic Checking; DMMRI


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Citation: Kulvinder Kochar Kaur., et al. “Path Directed towards a Stage when we almost Cure Type1 Diabetes Mellitus (T1dm) after a Century of Insulin Advent". EC Nutrition 4.6 (2020): 37-46.

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