Mini Review
Volume 4 Issue 5 - 2020
Dark Chocolate as a Practical Replacement for White or Milk Chocolate in Patients Coping with Overweight, Obesity, Type 2 Diabetes, and Metabolic Syndrome
Nicholas A Kerna1*, Uzoamaka Nwokorie2,3, John V Flores4,5, Jerome Adadzi3 and Rashad Roberson3,6
1SMC–Medical Research, Thailand
2University of Health and Humanities, Tortola, BVI
3University of Science, Arts and Technology, Montserrat, BWI
4Beverly Hills Wellness Surgical Institute, USA
5Orange Partners Surgicenter, USA
6R&R Rehab Associates, Georgia, USA
*Corresponding Author: Nicholas A Kerna, POB47 Phatphong, Suriwongse Road, Bangkok, Thailand 10500.
Received: April 06, 2020; Published: April 30, 2020


Two of the most consequential challenges facing an overweight, obese, diabetic, or metabolic syndrome (MetS) patient are dietary and lifestyle changes. For those patients that regularly consume chocolate or “chocoholics”, physicians and healthcare providers should consider dark chocolate as a practical replacement in overweight, obese, diabetic and MetS patients. Pure dark chocolate has no sugar or milk fat. Also, it is high in antioxidants and flavonols, that have demonstrated benefits to the cardiovascular system, lowering blood pressure, and mitigating the long-term risk of cancer, heart attack, and stroke. This review compares the constituents of the three varieties of chocolate (white, milk and dark chocolate). It presents a case that dark chocolate is the healthier of the three and should be considered a practical replacement for white or milk chocolate in patients coping with overweight, obesity, type 2 diabetes, and metabolic syndrome.

Keywords: Chocolate; Caffeine; Cardiovascular; Cocoa; Dark Chocolate; Diabetes, Flavon, High Blood Pressure


  1. Hollenberg NK., et al. “Flavanols, the Kuna, Cocoa Consumption, and Nitric Oxide”. Journal of the American Society of Hypertension 2 (2009): 105-112.
  2. McCullough ML., et al. “Hypertension, the Kuna, and the epidemiology of flavanols”. Journal of Cardiovascular Pharmacology 2 (2006): S103-S121.
  3. Katz DL., et al. “Cocoa and Chocolate in Human Health and Disease”. Antioxidants and Redox Signaling 10 (2011): 2779-2811.
  4. Miller KB., et al. “Survey of commercially available chocolate- and cocoa-containing products in the United States. 2. Comparison of flavan-3-ol content with nonfat cocoa solids, total polyphenols, and percent cacao”. Journal of Agricultural and Food Chemistry 19 (2009): 9169-9180.
  5. Alemanno L., et al. “Localization and identification of phenolic compounds in Theobroma cacao L. somatic embryogenesis”. Annals of Botany 4 (2003): 613-623.
  6. Baharum, Z., et al. “Theobroma cacao: Review of the Extraction, Isolation, and Bioassay of Its Potential Anti-cancer compounds”. Tropical Life Sciences Research 1 (2016): 21-42.
  7. Magkos F., et al. “Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification”. Annual Review of Nutrition 29 (2009): 223-256.
  8. Full Report (All Nutrients): 45105386, White Chocolate, UPC: 8435070421523. U.S. Department of Agriculture (2017).
  9. Full Report (All Nutrients): 45100254, Milk Chocolate, UPC: 099482439095. U.S. Department of Agriculture (2018).
  10. Full Report (All Nutrients): 45169407, 85% Dark Chocolate, UPC: 850686003358. U.S. Department of Agriculture (2018).
  11. Keen CL., et al. “Cocoa antioxidants and cardiovascular health”. American Journal of Clinical Nutrition 1 (2005): 298S-303S.
  12. Steinberg FM., et al. “Cocoa and chocolate flavonoids: implications for cardiovascular health”. Journal of the American Dietetic Association 2 (2003): 215-223.
  13. Schulte EM., et al. “Which foods may be addictive? The roles of processing, fat content, and glycemic load”. PLoS ONE2 (2015): e0117959.
  14. Leitner DR., et al. “Obesity and Type 2 Diabetes: Two Diseases with a Need for Combined Treatment Strategies - EASO Can Lead the Way”. Obesity Facts 5 (2017): 483-492.
  15. Shah SR., et al. “Use of dark chocolate for diabetic patients: a review of the literature and current evidence”. Journal of Community Hospital Internal Medicine Perspectives4 (2017): 218-221.
Citation: Nicholas A Kerna., et al. “Dark Chocolate as a Practical Replacement for White or Milk Chocolate in Patients Coping with Overweight, Obesity, Type 2 Diabetes, and Metabolic Syndrome”. EC Diabetes and Metabolic Research 4.5 (2020): 47-51.

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