Research Article
Volume 4 Issue 5 - 2020
Cost-Effectiveness of Comprehensive Screening of General Population for Hypertension: Can it Save Money and Life? Systematic Review of Pharmacoeconomic Studies
Majid Davari, Mende Mensa Sorato* and Shekoufeh Nikfar
Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Iran
*Corresponding Author: Mende Mensa Sorato, Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Iran.
Received: April 15, 2020; Published: April 28, 2020


Background: Hypertension is one of the major modifiable risk factors contributing for development of ischemic heart disease, diabetes, kidney disease, cerebrovascular disease and peripheral arterial disease. Early screening, detection and treatment of hypertension is effective for control of the disease progression. However, there is no robust evidence on whether screening general population for hypertension is cost-effective or not. Therefore, this systematic review was conducted to generate evidence on cost effectiveness of population-based screening for hypertension.

Methods: PubMed/Medline, Scopus, Web of sciences and Google Scholar were searched from January 2000 to 11 December 2019. Two investigators independently selected and reviewed pharmacoeconomic studies.

Results: Eleven studies were included in this review. All studies showed that screening people who are 40 years or older with high risk for cardiovascular disease is cost-effective. Screening of general adult population for hypertension is not-cost effective. Screening in developing countries is challenged by limited access to health care, in adequate health task force, poor financial protection and low health literacy of the population. Integrating multiple interventions, task shifting and using local opportunities for addressing the target population are important possibilities to improve opportunistic screening.

Conclusion: There is no adequate evidence to recommend screening of asymptomatic adults with no risk factor hypertension. Screening high risk populations aged 40 years and older at least annually is cost-effective in reducing hypertension and associated cardiovascular disease morbidity and mortality in developed and developing countries. Therefore, more strong economic evaluations from different perspectives are required to recommend general screening for hypertension.

Keywords: Screening Asymptomatic Populations; Hypertension; Cardiovascular Disease; Developing Countries


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Citation: Mende Mensa Sorato., et al. “Cost-Effectiveness of Comprehensive Screening of General Population for Hypertension: Can it Save Money and Life? Systematic Review of Pharmacoeconomic Studies”. EC Diabetes and Metabolic Research 4.5 (2020): 13-25.

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