Review Article
Volume 4 Issue 4 - 2020
Cardiac Dysfunction in Diabetes
Kurtulus Karauzum, Irem Karauzum and Tayfun Sahin*
Department of Cardiology, Medical Faculty, Kocaeli University Kocaeli, Turkey
*Corresponding Author: Tayfun Sahin, Department of Cardiology, Medical Faculty, Kocaeli University Kocaeli, Turkey.
Received: February 17, 2020; Published: March 20, 2020




Abstract

In the worldwide, the burden of diabetes mellitus (DM) and its associated complications are currently markedly increasing. These patients are at significantly higher risk of developing heart failure (HF) independent from other risk factors such as hypertension, coronary artery disease (CAD) and dyslipidaemia. The pathophysiology and pathogenesis of cardiac dysfunction in diabetic patients are still unclear. On the other hand, it has been currently demonstrated that impaired cardiac functions is associated with several mechanisms such as insulin resistance, hyperinsulinemia, longstanding hyperglycaemia-associated metabolic and oxidative stress, microvascular dysfunction, lipotoxicity, and cardiac autonomic neuropathy. The development of cardiac dysfunction due to DM is defined as ‘’diabetic cardiomyopathy’’ (DCM). The clinical manifestations of DCM may present from asymptomatic ventricular dysfunction overt HF. The most frequently used diagnostic methods are standard echocardiography and cardiac magnetic resonance imaging. A tight glycaemic control appears to play the central role for prevention and treatment of DCM. The management of DCM also includes lifestyle modifications, metabolic modulators, lipid-lowering therapy, treatment of coexistent hypertension or CAD, and medications for HF if presents. In this article, we aimed to provide a short review on the definition, classification, pathophysiology, diagnosis and management of DCM.

Keywords: Diabetic Cardiomyopathy; Heart Failure; Echocardiography

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Citation: Tayfun Sahin., et al. “Cardiac Dysfunction in Diabetes”. EC Nutrition 4.4 (2020): 06-14.

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