Research Article
Volume 4 Issue 2 - 2020
Correlation of Vitamin D with HbA1c and Ejection Fraction in CAD Diabetic and Non CAD Diabetic Patients in Northern India
Vinay Singh1*, Sandeep Garg1, Pramod Lali2 and Dinesh Dhanwal3
1Department of Medicine, Maulana Azad Medical college, New Delhi, India
2Department of Biochemistry, Maulana Azad Medical College, New Delhi, India
3Department of Endocrinology, NMCSH, Abu Dhabi, United Arab Emirates
*Corresponding Author: Vinay Singh, Department of Medicine, Maulana Azad Medical College, New Delhi, India.
Received: January 20, 2020; Published: January 29, 2020


Aim: To find out the correlation of Vitamin D levels with HbA1c in diabetic patients and with HbA1c and Ejection Fraction in CAD diabetic patients in Northern India.

Methodology: Study included 80 type 2 diabetic patients with age 50 years and above. These patients were equally divided into two arms, CAD diabetic and Non CAD diabetic based on clinical features, assessment and medical history. Group 1 was having T2DM + CAD positive patients (N = 40) and Group 2 was having T2DM patients (N = 40). Clinical and biochemical parameters including blood sugar, lipid profile were done in all patients. CAD was diagnosed on the basis of history and with criteria of low Ejection Fraction on 2D Echo. Vitamin D levels and HbA1c in all these patients were measured and were correlated with Ejection Fraction.

Results: Vitamin D levels were on the lower side in CAD diabetic (15.4 ± 4.95) group than in Non CAD diabetic group (20.88 ± 9.98). Out of the 80 patients investigated Vitamin D deficiency was observed in 36 patients in the CAD diabetic group (N = 40) and the same was only 18 in the Non CAD diabetic group (N = 40). Mean HbA1c (8.61 ± 1.55) was on the higher side in the CAD diabetic group when it was compared to Non CAD diabetic (8.01 ± 1.02) group. The value of correlation in between Vitamin D and HbA1c in CAD diabetic group was -0.076. In a CAD diabetic group mean Ejection Fraction was 38.6 ± 5.85. The r value of correlation between Ejection Fraction with HbA1c and Vitamin D was -0.013 and 0.25 respectively.

Conclusion: Vitamin D levels and Ejection Fraction show inverse correlation with HbA1c levels in CAD diabetic group. Also, Ejection Fraction was directly proportional to Vitamin D levels in CAD diabetic patients. 

Keywords: Vitamin D; CAD; T2DM; Ejection Fraction


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Citation: Vinay Singh., et al. “Correlation of Vitamin D with HbA1c and Ejection Fraction in CAD Diabetic and Non CAD Diabetic Patients in Northern India”. EC Nutrition 4.2 (2020): 01-07.

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